AUTOIMMUNE THYROIDITIS IN PREGNANCY- A CROSS SECTIONAL STUDY IN A TERTIARY CARE HOSPITAL OF SOUTHERN ODISHA
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2019, Vol 8, Issue 2
Abstract
BACKGROUND A lot of physiological changes occur during pregnancy due to complex endocrine and immunological alterations. Autoimmune thyroid dysfunction is quite common which is responsible for various fetomaternal complications. There are few Indian studies regarding thyroid autoimmunity. Hence study was taken to assess the prevalence of autoimmune thyroiditis in this part of India. Aims and Objectives- To know prevalence of autoimmune thyroiditis in pregnancy by estimating TPO Ab, FT4, FT3, S.TSH Study Design- Cross Sectional Study MATERIALS AND METHODS This study was done taking 1000 pregnant women attending antenatal clinic from October 2015 to November 2016 fulfilling inclusion and exclusion criteria, irrespective of gravida and trimester. They were screened for FT3, FT4, S. TSH and TPOAb. RESULTS Mean Age of presentation was 25.87 + 4.06. 17.3% of the patients were TPOAb positive. TPOAb levels vary from 69 IU/mL to 1300 IU/mL with a mean level of 173.13 + 145.82. TPOAb level > 35 IU/mL was taken as positive. Amongst these, majority 12% were euthyroid, 4.7% were hypothyroid, 0.6% were hyperthyroid. There was no significant difference in multi or primigravida. But more patients were in 2nd Trimester of pregnancy. CONCLUSION There is a significant prevalence of thyroid autoimmunity in this part of country that is 17.3 % in comparison to western countries where it is 6.5 %. Hence screening of all pregnant women for thyroid autoimmunity is suggested to avoid fetomaternal complications.
Authors and Affiliations
Rini George, Namita Mohanty, Sijoy Kurian
Keywords
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- EP ID EP553069
- DOI 10.14260/jemds/2019/26
- Views 70
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