A Study of Correlation of Urine Microalbuminuria and eGFRwith CD4 Count in HIV Patients
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 3
Abstract
HIV infection is most ofteen associated with renal abnormalities. This study was conducted in 100 HIV patients including newly diagnosed and on patients on ART. The study population were divided into 4 groups according to CD4 count and GFR. About 58% of study population were in the age group of 21-40 years and 38% of study population were in the age group of 41-60 years. Most of the population in the study group were in the age group of 21-36 years. Male population is around 77% and female population is around 23% in this study population. Most of the population were on ART therapy. Urine microalbuminuria, macroalbuminuria,puscells,red cells and ultrasound abdomen and pelvis were performed in these patients. Urine microalbuminuria(41%) and macroalbuminuria(20%),Ultrasound evidence of increased cortical echoes(11%) and pyelonephritis/cystitis(10%) were most prevalent in study population and the p value was <0.001,statistically significant and were seen most commonly in HIV patients receiving antiretroviral therapy.other abnormalities like presence of hematuria,casts and ultrasound evidence of contracted kidney with loss of corticomedullary differentiation were seen in only few patients which were statiscally not significant.These renal abnormalities were more prevalent in stages 3 and 4 of CD4 count <200cells/microliter and in stages 3 and 4 of GFR <60ml/min//m2. There is a positive linear correlation between prevalence of urine microalbuminuriawith fall in CD4 count and GFR.
Authors and Affiliations
Dr P B Sriram MD, Dr B Palanikumar MD
Keywords
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- EP ID EP595897
- DOI 10.9790/0853-1603058995
- Views 72
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