A Study of Gall Stone Disease with Special Reference to H. Pylori Infections in a Tertiary Care Centre in India
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 8
Abstract
To find out the various clinicopathological presentations of gall stone disease with special relation to H,pylori infections of Gall Bladder. Institution based prospective observational study in a tertiary care centre. Study was conducted on patients who attended the department of General Surgery of Medical College Kolkata. A total of 50 patients were taken up for the study. Rapid urease test of the gall bladder mucosa was positive in 5 out of 10 male patients (50%) who were admitted with chronic calculus cholecystitis. Rapid urease test was positive in 17 out of 40 female patients (42.5%) who were admitted with chronic calculus cholecystitis. So total 22 patients out of 50 (44%) were affected with H. Pylori infections. IgG antibody kit test were positive in 3 out of 10 male patients (30%) who were admitted with chronic calculus cholecystitis. IgG kit test were positive in 7 out of 40 female patients (17.5%). Total 10 out of 50 patients (20%) with chronic calculus cholecystitis were IgG positive i.e. chronic H.Pylori infections. The identification of H Pylori antibody IgG in serum and H Pylori infection in gallbladder and pathological changes in gallbladder among the patients with gallstones provides a strong evidence of association of the organism with chronic calculus cholecystitis or gallstone diseases and H Pylori may be an etiological agent in gallstone formation. Further studies required to determine its role in gall bladder cancer formation
Authors and Affiliations
Dr. Chandan Roy Choudhury, Dr. Puranjoy Saha, Dr Prasanta Kumar Das, Dr. Susanta Sarkar, Dr. Satya Prakash Kuila
Keywords
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