A study of interaction of cigarette smoke with alpha-1 antitrypsin and adenosine deaminase in patients of chronic obstructive pulmonary diseases (COPD) and antioxidant role of vitamin E
Journal Title: International Journal of Clinical Biochemistry and Research - Year 2018, Vol 5, Issue 4
Abstract
Lungs are the only organs which are continuously exposed to external environment through the process of breathing The cigarette smoking is main leading cause of various morbidities related to lungs Adenosine deaminase ADA and alpha1 antitrypsin A1AT are the two very important parameters of which ADA is required for maintaining proper immunity and A1AT is required for resolving oxidant stress on lungs by various mechanism In the present study we evaluated the level of these parameters in active cigarette smokers without lung disease and COPD patients and found that ADA level was significantly high in healthy smokers and COPD patients as compared to healthy controls PKeywords Adenosine deaminase Alpha1 antitrypsin Chronic obstructive pulmonary diseases COPD Vitamin E and Cigarette smoke CS
Authors and Affiliations
Dhananjay V Andure, Anita M. Raut, Ramchandra K. Padalka, Sangita M. Patil, Sonali S. Bhagat
Keywords
Related Articles
- EP ID EP475423
- DOI 10.18231/2394-6377.2018.0111
- Views 76
- Downloads 0
Comparison of LDL-cholesterol estimated by various formulae with directly measured LDL-cholesterol in a tertiary care centre of Maval Taluka
Introduction Lowdensity Lipoprotein Cholesterol LDLC concentration in blood gives indication of cardiovascular disease risk LDLC may vary at various strata of Triglycerides and in metabolic diseases like Diabetes Mellitu...
Dyslipidemia correlating with reduced glomerular filtration rate in apparently healthy individuals
There are many studies relating the renal dysfunction with dyslipidemia. This study intended to assess the correlation of estimated glomerular filtration rate (eGFR) with the lipid levels in apparently healthy individual...
Effect of adenosine deaminase activity on lipid profile in patients of type 2 diabetes mellitus
Background: Type 2 diabetes mellitus is a worldwide endemic disease. Dyslipidemia is also a frequent disorder associated with diabetic patients. The present study is an attempt to link that elevated levels of adenosine d...
MDM2 promoter polymorphism (rs2279744) and serum estrogen level are associated with increased risk of epithelial ovarian cancer: A case-control study
Introduction Epithelial ovarian cancer EOC is most common malignancy affecting Indian women One of the transcriptional targets of p53 is human homolog of Murine Double Minute 2 Oncogene MDM2 which is a crucial negative r...
A study to evaluate the vitamin D status in rheumatoid arthritis patients
Introduction: Vitamin D deficiency has been shown to be associated with autoimmune diseases, which is a controversial finding in various previous studies. Moreover there are limited studies done on serum vitamin D and it...