Dyslipidemia correlating with reduced glomerular filtration rate in apparently healthy individuals
Journal Title: International Journal of Clinical Biochemistry and Research - Year 2017, Vol 4, Issue 2
Abstract
There are many studies relating the renal dysfunction with dyslipidemia. This study intended to assess the correlation of estimated glomerular filtration rate (eGFR) with the lipid levels in apparently healthy individuals. A total of 211 people with normal serum creatinine and no previous history of cardiovascular disease or renal disease were selected. Hypercholesterolemia and hypertriglyceridemia are now being reported as risk factors for progression of renal disease. Recently it has been studied that a rise in apolipoprotein B rich lipoproteins to be associated with decline in renal function. In this study there was a significant negative correlation of Low Density Lipoprotein (LDL) and total cholesterol with e GFR. There was a positive correlation with High Density Lipoprotein (HDL) and negative association with non HDL cholesterol. However larger cohort studies are required to establish dyslipidemia as a causative factor for renal dysfunction.
Authors and Affiliations
V. Malarkodi, M. Malathi
Keywords
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- EP ID EP296960
- DOI 10.18231/2394-6377.2017.0046
- Views 61
- Downloads 0
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