A Study of Intracervical PGE2 Gel for Cervical Ripening and Induction of Labour
Journal Title: International Journal of Contemporary Medical Research - Year 2018, Vol 5, Issue 3
Abstract
Introduction: Labor is a process through which the fetus moves from the intrauterine to extrauterine environment. Induction of labor is defined as the initiation and perpetuation of uterine contractions with the goal of producing progressive cervical effacement and dilatation. Induction of labor is common in obstetric practice. Study aimed to evaluate the efficacy of intracervical Prostaglandin E2 gel as a cervical ripening agent in unfavorable cervix for induction of labor. Material and Methods: This study comprised of 180 women who required labor induction Singleton pregnancy between 37- 41 weeks live intrauterine fetus, Cephalic presentation, Bishop score of 1-6, Reactive FHR pattern were included. Those women who required only single induction and who delivered within 24 hours were categorized as Group 1. Women with persistent poor Bishop score < 6 after 24 h were re-induced and belonged to Group 2. Results: Both the groups were comparable in demographic factors like age and period of gestation. The most common indication for induction was past dates followed by prelabor rupture of membranes and gestational hypertension. In group 2, 48.4% was induced for past dates. Reinduction was required in 41.5% of primi and 18% of multigravida. Success rate in group 1 was71.6% and in group 2 was 42%. Maternal side effects were minimal and neonatal outcome was good. Conclusion: The study showed that intracervical application of PGE2 is effective, safe and acceptable method for labor induction in women with unfavorable cervix. Dinoprostone gel application resulted in improved Bishops score and decreased caesarean delivery rate. All these effects were achieved without increasing maternal and neonatal morbidity.
Authors and Affiliations
Niloufur Syed Bashutheen, Minthami Sharon
Keywords
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