A STUDY OF RELATION BETWEEN SYMPTOMS AND FEV1 (FORCED EXPIRATORY VOLUME IN ONE SECOND) IN PATIENTS WITH COPD AND BRONCHIAL ASTHMA
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 47
Abstract
BACKGROUND To study the background, clinical manifestations and relation between clinical symptoms and FEV1 (Forced Expiratory Volume in one second) in patients with chronic obstructive pulmonary disease and bronchial asthma. Clinical symptoms are in direct relation with COPD severity, but no relation with bronchial asthma in our study. MATERIALS AND METHODS Study Design- This is a hospital-based, cross-sectional study of patients with COPD and Bronchial asthma as defined by GOLD in 2015 and GINA in 2015; 47 patients with a diagnosis of COPD and 47 patients of Bronchial asthma attending the outpatient department or admitted in the medical wards/ICU of Government Fever Hospital/Guntur Medical College were examined and data were collected on a pretested proforma. A detailed history was taken and a thorough clinical examination was done in all patients. Five symptoms (cough, dyspnoea, wheeze, tightness of chest, nocturnal symptoms) were recorded on a two-point scale. Zero point was given for absence of symptom and one point for presence of symptom. A cumulative symptom score was calculated with a maximum score of five. Dyspnoea was also graded according to Modified Medical Research Council (MMRC) grading of dyspnoea. FEV1 was measured by spiroanalyser (Vitalograph), meeting the standard criteria. Spirometry was obtained with the patient seated and wearing nose clips. The best of three reproducible measurements was taken for analysis. The post-bronchodilator FEV1 was assessed at 20 minutes after the inhalation of 200 µg of salbutamol using a metered-dose inhaler with a spacer device. The descriptive statistics was done to describe FEV1 and other data symptoms in both COPD and Bronchial asthma patients. The data was analysed using Excel and SPSS version 20. The results were expressed in terms of percentage, means and standard deviation, and relevant tests of significance like Independent sample “t” test were applied and p < 0.05 was considered as statistically significant. RESULTS The procedure workup consists of clinical history along with chest x-ray and spirometry. If both of them satisfied the inclusion and exclusion criteria, then routine investigations like blood investigations and spirometry results were compared for Asthma and Chronic obstructive pulmonary disease. CONCLUSION Our study emphasises the importance of using objective assessment of lung function in both Bronchial asthma and COPD patients prior to implementation of medical treatment strategies. There is a statistically significant difference between COPD and Bronchial Asthma for FEV1 pre, FEV1 post and Total Score (p < 0.05).
Authors and Affiliations
Damaraju Seshagirirao, Juvvala Kishan Srikanth
Keywords
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- EP ID EP217722
- DOI 10.14260/Jemds/2017/787
- Views 112
- Downloads 0
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