EFFICACY AND SAFETY OF MISOPROSTOL IN SECOND TRIMESTER MEDICAL TERMINATION OF PREGNANCY AT A TERTIARY LEVEL CENTRE IN KERALA
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 10
Abstract
BACKGROUND Second trimester MTP is done by various methods. Most commonly used and studied in various regimens of Mifepristone and Misoprostol by oral and vaginal routes. FIGO recommended various regimens. In our institute, we have noted even lesser doses of drugs without prolongation of induction expulsion interval, patient responded well. Hence, we conducted this study. MATERIALS AND METHODS This non-randomised clinical trial of various doses of Misoprostol for second trimester MTP conducted at family welfare unit of Govt. Medical College, Kozhikode, from 1.1.2017 to 31.12,2017. Consecutive patients who satisfy inclusion criteria were divided into 3 groups. All A, B and C group took 600 mg Mifepristone orally and 200, 600 and 800 ug vaginal Misoprostol respectively. After 48 hrs., data was analysed by SPSS 16.0. RESULTS Majority of second trimester abortion were for anomalous babies (89%) and 11% were for medico-legal issues; 600 ug Misoprostol had 90% success rate. CONCLUSION 600 mg Mifepristone followed by 600 ug Misoprostol had an induction expulsion interval of < 24 hrs. and equally efficacious too for the higher doses of Misoprostol regimens.
Authors and Affiliations
Mohammed Sidhiq Chundakkadan, Mini C. H
Keywords
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- EP ID EP411297
- DOI 10.14260/jemds/2018/277
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