A Study of Risk Factors of Clinically Significant Macular Edema in Diabetic Individuals
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 3
Abstract
To study the incidence of CSME in diabetic retinopathy & association of CSME with risk factors like duration of diabetes, glycemic control, hypertension, hypercholesterolemia, anemia and nephropathy, an observational cross sectional study was conducted over a period of 6 months in 96 patients of diabetic retinopathy. After recording blood pressure, blood investigations were done and the significance of risk factors was compared in both the groups [with CSME and without CSME]. Mean Duration of Diabetes among the CSME group (10.61± 4.259 years) was significantly higher than the non-CSME group (7.60 ±3.65 years). Serum cholesterol in the CSME group [241.76±13.021mg%] was significantly higher compared to the nonCSME group [187.52±10.465mg%]. Serum LDL in the CSME group [139.79±13.291mg%] was significantly higher than the non-CSME group [100.45±8.714mg%]. FBG in the CSME group [191.55±62.233 mg%] was significantly higher compared to the non-CSME group [145.5±50.311 mg%]. Glycosylated haemoglobin, HbA1c was significantly higher in the CSME group [9.19±0.919mmol/L] as compared to the non-CSME group [7.38±0.834mmol/L]. The haemoglobin level was lower in the CSME group [9.61±0.608 g%] as compared to the non-CSME group [11.15±0.770 g%]. The urea and creatinine level were significantly higher in the CSME group. The urea levels in the CSME and non-CSME group were [46±31.631] and [35.97±10.550] whereas the creatinine levels were [1.32±0.778mmol/L] and [0.91±0.299mmol/L] respectively. In conclusion, high cholesterol and high HbA1c levels were the two most important risk factors that lead to the development of CSME in this study. Anemia and low hematocrit have been found to be associated with microvascular complications including diabetic macular oedema. Serum urea and creatinine level, which reflects the renal function, were significantly higher in the CSME group
Authors and Affiliations
Dr. P. Rajasekhar, Dr. M. Parni Kumar, Dr. J. Sahithi
Keywords
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- EP ID EP600223
- DOI 10.9790/0853-1603100608.
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