A study of Serum lipids among children suffering from nephrotic syndrome

Journal Title: Medpulse International Journal of Pediatrics - Year 2019, Vol 9, Issue 1

Abstract

Background:Hyperlipidemia is a common findings in nephrotic syndrome. Thereis increased total Cholesterol, LDL Cholesterol, VLDL cholesterol and lower normal HDL Cholesterol. There is paucity of studies on derangement ofserum lipids with nephrotic syndrome in Indian children. Hyperlipidemia isusually observed during the active phase of disease and disappears with resolution of proteinuria. Objective: A study of Serum lipids among children suffering from nephrotic syndrome. Materials and Methods:A Prospective study was conducted at Basaveshwara Medical College, Chithradurga from January 2018 to June 2018. A total of 60 cases of children with nephrotic syndrome who were admitted for the first time in the pediatric ward our hospital was included in the study.Their clinical status was confirmed by clinical examination and laboratory tests includingurine examination for protein, blood urea, serum cholesterol and serum proteins study included.Results: In our study nearly 76.7% of the study subjects were less than 6 years and 23.3% of them were between the 7 to 12 years.In our study the overall total Cholesterol level, LDL Cholesterol, VLDL Cholesterol, and Triglyceride were found to be much higher than the controls and the association was found to be statistically very significant. Among the cases with steroid sensitive Nephrotic Syndrome the mean cholesterol level was found to be 429.6 mg/dl and 685.9 mg/dl in Steroid Resistant Nephrotic syndrome. Conclusion:Our study concludes that, in nephrotic syndrome, there is generalized hyperlipidemia (except HDL).persistent elevation in the cholesterol levels, which may predispose to development of atherosclerosis and progression to chronic renal failure.

Authors and Affiliations

Srinivasa V, Lakshmi L

Keywords

Related Articles

Clinical profile and outcome of newborn babies admitted to SNCU a level 2 neonatal intensive care unit

The neonatal period is the most vulnerable period for child as they are high risk for mortality. Data regarding a total of 877 neonates were admitted to SNCU during the study period of one year between January 2017- Dece...

A study of various risk factors associated with development of severe respiratory distress in the new born at tertiary health care center

Background: Neonatal respiratory distress occurs in infants whose lungs have not yet fully developed. The earlier a baby is born, the less developed the lungs are and the higher the chance of neonatal respiratory distres...

Study to assess conditions associated with xerophthalmia and compliance of VADD control programme among children in rural area of Salem

Background: As a vitamin, A deficiency progresses, the epithelial tissues of the eye become severely altered. Xerophthalmia is a very characteristic lesion of Vitamin A deficiency. The plasma retinol level is not an accu...

A study of clinico-demographic profile and factors associated with the patients of measles at tertiary health care center

Background: After Eliminating Polio from county our next Aim toward Measles. Measles, also known as rubeola, Measles is a highly infectious but preventable disease with potential for eradication but is still responsible...

Download PDF file
  • EP ID EP443927
  • DOI 10.26611/10149110
  • Views 105
  • Downloads 0

How To Cite

Srinivasa V, Lakshmi L (2019). A study of Serum lipids among children suffering from nephrotic syndrome. Medpulse International Journal of Pediatrics, 9(1), 33-35. https://europub.co.uk/articles/-A-443927