A study of Serum Soluble CD40 Ligand level and its correlation with serum CK-MB and lipid profile in patients with acutecoronary syndrome
Journal Title: IP International Journal of Maxillofacial Imaging - Year 2018, Vol 5, Issue 2
Abstract
Introduction: Coronary heart disease is an impairment of heart function due to inadequate blood flow to the heart. It is the most common cause of death worldwide. Serum sCD40L is an inflammatory marker. It is released from the platelets as soon as the onset of the chest pain. It is a strong predictor of cardio vascular risk factor. Objectives: To estimate Serum sCD40Ligand, Serum CK-MB, Serum Lipid Parameters, Serum LDH, and Serum AST levels in patients with ACS. Materials and Methods:Study group comprised of 50 subjects were admitted in ICCU with ACS. 50 healthy sex and age matched subjects were taken as control groups. Venous blood samples were collected. Serum Soluble CD40Ligand was estimated by ELISA technique, Serum CK-MB estimated by Immunoinhibition method, Serum Lipid profile by enzymatic assay methods. Serum LDH by DKGC method, Serum AST by Modified IFCC method. Results:There was significant increase in Serum sCD40L(p<0>significant decrease in the Sr. HDL-C levels in the ACS patients compared to control group. There was no significant change in Sr. LDH levels and Sr. AST levels in ACS patients compared to control group. There was a significant positive correlation between Serum sCD40L and Serum CK-MB, Serum TC, Serum TGL, Serum LDL-C, Serum VLDL and a negative correlation between Serum sCD40L and Serum HDL-C while no significant correlation was found between Serum sCD40L with Serum LDH and Serum AST levels. Conclusion:Serum sCD40L can be used as a marker in individuals with Acute Coronary Artery disease.
Authors and Affiliations
M. Manonmani, V. Kuzhandai Velu, Manimekalai K
Keywords
Related Articles
- EP ID EP472701
- DOI 10.18231/2394-6377.2018.0036
- Views 69
- Downloads 0
Association of serum adiponectin levels with albuminuria among type 2 diabetes mellitus patients
Arterial blood gas (ABG) analysis is a challenging but clinically very important diagnostic test in intensive care unit patients but combined acid base disorders either due to compensatory mechanisms or mixed disorders a...
MRI 3D CISS: A Boon for Neuro Imaging
The cerebrovascular system plays a key role in supporting the brain by providing oxygen and nutrients. The coupling between neuronal activity and vascular response is controlled by the neurovascular unit (NVU). Dysfuncti...
Giant complex odontomas erupting in the Oral Cavity
Odontomas are the most common odontogenic tumors. Complex odontomas are less frequently found as compared to the compound odontomas and they are considered to be hamartomatous malformations rather than true neoplasms. Us...
Radiographic Quality of root fillings performed by dentists in Jammu and Kashmir, North India
The present study aimed at assessing the quality of root canal obturations being performed in the state of Jammu and Kashmir. Records of 1056 endodontically treated teeth from patients who visited the department of Conse...
Ultrasonography in maxillofacial Imaging – a review
Ultrasonography is being currently used in imaging of various head and neck pathologies owing to its non-invasive nature and has gained wider acceptance in maxillofacial imaging. In this paper we will take a relook of Ul...