Correlation of trace elements (serum zinc and copper) in type 2 diabetic patients with and without complications
Journal Title: IP International Journal of Maxillofacial Imaging - Year 2018, Vol 5, Issue 2
Abstract
Introduction: Type 2 diabetes mellitus (DM) is supposed to be associated with alteration in the serum levels of trace elements. Conversely, research also suggests that imbalances of specific elements associated with the complications of diabetes mellitus. Copper plays important role in oxidative stress and it’s one of the important factor contributes to aetiology of DM. And zinc involved with synthesis & secretion of insulin. So, we have choose copper and zinc to find association in diabetics patients. Materials and Methods: In this cross sectional observational study total of one hundred and twenty (120) subjects were included and categorized into 3 groups. On the basis of screening, 80 patients were divided into two study groups: Group I (40 patients with micro- or macrovascular complications) and Group II (40 diabetic patients without complications). Group III include the 40 age and sex matched non-diabetic healthy control subjects selected for comparison. Serum zinc, copper concentration and HbA1c% (glycated haemoglobin) were estimated in all three study groups. Result: Serum copper concentration and HbA1c% were significantly (p<0> Conclusion: Alteration in levels of trace elements (like, Zn and Cu) are found to be important influencing factors for diabetic patients for developing complications. From the present study, it may be determined that altered levels of trace elements (like zinc and copper) may have contributory a role in the pathogenesis and progression of type 2 DM.
Authors and Affiliations
Hiren Sanghani, Vijaysinh Parmar, Asha Khubchandani
Keywords
Related Articles
- EP ID EP472904
- DOI 10.18231/2394-6377.2018.0051
- Views 60
- Downloads 0
Markers of atherosclerotic risk in patients with non-alcoholic fatty liver disease: A preliminary study
Introduction: The prevalence of Non-Alcoholic Fatty Liver Disease (NAFLD) is rising continuously. Cardiovascular disease is one among the leading causes of morbidity and premature mortality in patients with NAFLD. Aims...
Prenatal diagnosis: A cytogenetic approach
Prenatal diagnosis is offered to patients at risk of chromosome anomalies with Abnormal ultrasound scan, Carrier of a chromosomal structural rearrangement and Elevated risk of aneuploidy indicated by biochemical and/or u...
Bilateral Tonsillolith – An incidental finding
A calcified mass within the tonsil is called as Tonsillolith and it is a relatively rare entity commonly found in the tonsillar crypt. They are usually single and unilateral, but occasionally may be multiple or bilateral...
Estimation of the age of senegalese children based on panoramic radiography of the third mandibular molar
Introductionnbsp The objective of this preliminary study was to evaluate the interest of the third molar in the determination of the age of Senegalese subjects by the Demirjian methodMaterials and Methods This is a descr...
Morphometric evaluation of Bizygomatic distance and maxillary sinus width as dimorphic tool- A CBCT study
Objectives: The objective of this study is to determine the age prediction on the basis of Bizygomatic distance, intermaxillary distance, Antero-Posterior diameter and maxillary sinus width. The bizygomatic distance and...