Markers of atherosclerotic risk in patients with non-alcoholic fatty liver disease: A preliminary study
Journal Title: IP International Journal of Maxillofacial Imaging - Year 2018, Vol 5, Issue 2
Abstract
Introduction: The prevalence of Non-Alcoholic Fatty Liver Disease (NAFLD) is rising continuously. Cardiovascular disease is one among the leading causes of morbidity and premature mortality in patients with NAFLD. Aims and Objectives: To determine the risk of atherosclerosis in NAFLD subjects diagnosed by USG at K.S.Hegde Charitable hospital. Materials and Methods:A cross-sectional study involving 203 persons diagnosed with NAFLD were included in the study. Subjects with alcoholic liver disease, renal failure, tuberculosis, hepatitis B and/or C and those on lipid lowering drug were excluded from the study. Lipid profile was measured and Atherogenic Index of Plasma (AIP) was calculated as log (TG/HDL-c). Categorization of the subjects with respect to risk of atherosclerosis was done based on serum LDL-c, non HDL-c and AIP. Statistical analysis was done using Chi Square test and p value < 0> Results: More than normal values were observed for serum total cholesterol, LDL-c, triglyceride and non HDL-c in high percentage of NAFLD subjects (76.8%, 84.7%, 70.4% and 72.4% respectively). Serum HDL-c level was low in 53.2% subjects. 51.2% of subjects had high AIP and 23.6% had moderately high AIP. Conclusion: Results of categorization of the subjects with respect to risk of atherosclerosis based on serum LDL-c, non HDL-c and AIP showed that high percentages of subjects were in moderate and high risk categories. AIP is probably a better marker to determine the risk of atherosclerosis.
Authors and Affiliations
Roopa Rani Bhandary, Sukanya Shetty, Ashalatha Rao, Srikrishna U
Keywords
Related Articles
- EP ID EP474167
- DOI 10.18231/2394-6377.2018.0068
- Views 80
- Downloads 0
Comparative study of serum copper, zinc, Cu/Zn ratio in pulmonary tuberculosis patients with normal subjects
Introduction: Tuberculosis (TB) is an important global health problem. It has more impact on developing and underdeveloped countries. The impact of tuberculosis can be seen by the fact that in 1993, the world Health Orga...
Determination of age and gender using condylar height and coronoid height- An orthopantomographic study
Introduction The determination of age and gender in remnants of skull is important for medicolegal cases especially where the bodies have been injured beyond identification as seen usually in cases of mass disaster Panor...
Radiation induced oral mucositis – A case report with review of literature
Oral mucositis is a frequently occurring and debilitating complication of radiation therapy for head and neck cancer It is an early effect of radiation and results from mitotic death of the basal cells of the oral epithe...
Use of deproteinizer to eliminate interference of high bilirubin on measurement of serum creatinine by the kinetic jaffe reaction
Introduction: Serum creatinine is a useful diagnostic parameter of kidney function. Its concentration reflects glomerular filtration rate. Because of negative interference of bilirubin over creatinine level, may mislead...
Evaluation of the frontal sinuses dimensions in sex estimation among a sample of adult Kashmiri population using multidetector computed tomography
Introduction Aim of the present study is to determine gender using morphometric measurements on the frontal sinuses MDCT scanMaterials and Methods The study included 100 subjects 50 males and 50 females For each particip...