A study of the clinical profile and outcome of spina bifida
Journal Title: International Journal of Medical Research & Health Sciences - Year 2016, Vol 5, Issue 2
Abstract
Neural tube defects (NTDs) are a group of congenital anomalies characterized by defects in dorsal midline structures, including neural tissue, dura, muscle, bone and/or skin. The clinical presentations and the follow-up of these patients requires attention to various end organs besides the nervous system. To evaluate the clinical profile and surgical outcome of children with spina bifida. Out of a total of 74 patients treated at our institute for spina bifida between June 2013 to august 2015, 74 cases of spina bifida were analyzed retrospectively and prospectively. The clinical profile, radiological findings and urodynamic studies were recorded. Craniospinal MRI was done in patients to screen for Arnold Chiari malformations and monitoring of hydrocephalus was done as a management protocol at our institute for these children. All these patients except two underwent surgery for correction and closure of the spinal defect. Associated anomalies were treated accordingly. They were clinically assessed over a mean follow up period of 1.3 years, ranging from 2 months to 2½ years. 73% of the patients presented in the neonatal age group. Of which, 72% presented with a visible sac over the back.72% of the cases were Myelomeningocoeles. 79% of the defects were in the lumbosacral region. 30% presented with sensorimotor loss or bladder bowel incontinence. Sensorimotor improvement was seen in 12.5% after repairing the defect with the help of physiotherapy and braces. 30% of the patients were diagnosed to have hydrocephalus, of which 33% required a CSF diversion procedure. The postoperative course of spina bifida repair was found to be uneventful in 90% of the patients.
Authors and Affiliations
Theophilus Nikita Kumar
Body mass index and eating habits in young adults from Romania
This paper aims to investigate Body Mass Index, eating habits, knowledge and practices regarding this. Between 2013-2014 a self-administered questionnaire was used in sample of 1359 subject from urban area, aged 18-30 ye...
RPOB gene mutation in rifampicin resistant MRSA from foot infections of patients having diabetes mellitus
Staphylococcus aureus is an opportunistic bacterial pathogen associated with asymptomatic colonization of the skin and mucosal surfaces of normal humans. Staphylococcus aureus isolates are often multidrug resistant. Rifa...
Evaluating the effect of genistein on the amount of BDNF protein in the spinal cord of diabetic ovariectomized rats
BDNF (Brain derived neurotrophic factor) is a secretion protein and a member of the neurotrophin family of growth factors. Studies have shown that in ovariectomized animals, the expression of BDNF decreased. However, rec...
Physiological Study on the Relation of Heart Rate Variability in Ageing and Thyroid Hormone Disorder
The present study aimed to investigate whether cardiac autonomic dysfunction in aging human might be related to an underlying thyroid disturbance. ageing has been associated with hypothyroidism and cardiac autonomic dysf...
Iatrogenic lumbar Pseudomeningocele: A case report and review of literature
Lumbar pseudomeningocele is an uncommon complication of lumbar spine surgeries. This occurred due to extradural encapsulated cerebrospinal fluid collection after accidental durotomy or un-repairable dural tear. On review...