A study of the different treatment strategies and outcome of babies with meconium stained amniotic fluid

Journal Title: Medpulse International Journal of Pediatrics - Year 2017, Vol 3, Issue 1


Background: Meconium aspiration syndrome (MAS) is defined as respiratory distress in an infant born through meconium-stained amniotic fluid (MSAF) with characteristic radiological changes and whose symptoms cannot be otherwise explained.It causes respiratory difficulty secondary to airway obstruction, chemical irritation, infection and surfactant inactivation. Aims and Objectives: To study the different treatment strategies and outcome of babies born through meconium stained amniotic fluid Methodology: This prospective study was conducted in NICU of department of Paediatrics of tertiary care centre from 1st January 2015 to 30th June 2016. Total 152 neonates meeting the inclusion and exclusion criteria constituted the material for this study. Detailed history and clinical findings were recorded in the predesigned proforma. All babies with meconium stained amniotic fluid were taken into study irrespective of the gestational age were included into study. The statistical software namely Open epi-info was used for the analysis of the data and Microsoft Word and Excel have been used to generate graphs and tables etc. Result: Majority of the babies were asymptomatic, most of them improved with supplemental oxygen only. There was a strong association between Thick MSAF and MAS. Those babies who required immediate intubation and mechanical ventilation after delivery had a higher mortality rate. Conclusion: It can be concluded from our study that majority of babies with MSAF especially thin MSAF are asymptomatic and have a good outcome. Thick MSAF is associated with high chances of MAS and those babies who have severe MAS that require mechanical ventilation soon after birth have a poor outcome probably due to severe respiratory compromise and associated co-morbidities like severe birth asphyxia, sepsis and ventilator associated complications.

Authors and Affiliations

Deepa Sachin Phirke, Bhavesh Shah, Defairlin Ranee


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  • EP ID EP260356
  • DOI -
  • Views 110
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How To Cite

Deepa Sachin Phirke, Bhavesh Shah, Defairlin Ranee (2017). A study of the different treatment strategies and outcome of babies with meconium stained amniotic fluid. Medpulse International Journal of Pediatrics, 3(1), 28-31. https://europub.co.uk/articles/-A-260356