A Study of Thyroid Disorders in Third Trimester of Pregnancy
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 4
Abstract
Background: Thyroid disease is the second most common endocrine disease to affect women of reproductive age. Thyroid disorders can result into adverse reproductive and pregnancy implications. Although gestational hyperthyroidism is uncommon (0.2%), gestational hypothyroidism occurs in higher prevalence (2.5%) and can lead to neonatal and child neurodevelopmental deficits and maternal obstetric complications. Thyroid-related pathophysiologic changes aggravated by pregnancy. Trimester-specific reference intervals for thyroid function tests are critical for maintaining the delicate balance of thyroid hormones during pregnancy. Thyroid-stimulating hormone (TSH) levels are low-normal in the first trimester, with normalization by the second trimester and remains normal in third trimester also. Hypothyroidism during pregnancy is associated with gestational hypertension and low birth weight. Women with hyperthyroidism (high TSH levels) had a >3-fold increase in risk of very preterm delivery. Objective: To evaluate the prevalence of thyroid disorders in pregnancy. Methods: This was a observational study among the pregnant women attended the labour room for full term normal delivery. All the pregnant women who were registered at Community Health Centre for delivery along with results of TSH levels were considered as study subjects. Results: The present study revealed a prevalence of 2.32% of hyperthyroidism and a prevalence of 7.94% of hypothyroidism. The mean age of study subjects was 23.38 years ±3.60. The TSH levels were observed on different parameter like age, caste, parity etc. Most of the pregnant women were primiparous and 2nd gravida. Conclusions: Thyroid disorders are common in pregnancy, and the most common disorder is subclinical hypothyroidism. Early detection of Thyroid dysfunction can help in starting treatment in affected pregnancies, for better outcome. Hence, Thyroid function test must be advised to all pregnant women.
Authors and Affiliations
Mahesh Kumar Goyal, Gouri Bhaduri, Maheshwar Prasad
Keywords
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- EP ID EP534196
- DOI 10.21276/ijmrp.2018.4.4.007
- Views 108
- Downloads 0
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