A Study on Clinical Efficacy of Calcium Channel Blockers and Angiotensin Receptor Blockers in Hypertension with Left Ventricular Dysfunction
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 5
Abstract
Hypertension is often caused by the excessive extracellular fluid which consists of mean arterial blood pressure is greater than 110mmHg under resting condition is usually considered to be hypertensive and this level occurs when diastolic blood pressure is greater than 90mmHg and systolic blood pressure is greater than about 135-140mmHg .Patients who met the inclusion criteria visited to hospital with hypertension are collected Demographic details, chief complaints, lab data, medication chart, 2D echo imaging parameters are noted by using patient data collection form. In the present study we have enclosed 120 patients who met the inclusion criteria and parameters are collected from Physical examination, 2D-Echo imaging. The drugs recorded mainly those who are prescribed with amlodipine (CCB) and telmisartan (ARB) from case reports of patients. The mean differences for CCB’s and ARB’s followed as EDD(0.412 and 0.508),ESD(2.103 and2.270),EF(3.75 and 4.73),triglycerides(3.65 and 4.82),FS(3.05 and 5.2881),Systolic BP(27.76 and31.00),diastolic BP(16.92 and 19.00).In this study, we observed less regression for amlodipine when compared with telmisartan under similar conditions of blood pressure, as it is effective in protecting the progression of hypertension, LV hypertrophy and mild to moderate diastolic dysfunction. It mainly demonstrates the Initial use of calcium channel blockers in hypertensive patients might be superior to ARBs for prevention of stroke and MI events, independent of their antihypertensive effect.
Authors and Affiliations
S. Sindhuja
Keywords
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