A Study on Clinical Profile of Neonatal Seizures
Journal Title: International Journal of Contemporary Medical Research - Year 2018, Vol 5, Issue 7
Abstract
Introduction: The neonatal period is limited to the first 28 days of life in a term or preterm infants. Neonates are at particular risk for the development of seizures because metabolic, toxic, structural and infectious diseases are more likely to be manifested during this time than during any other period of life. Study aimed to know the etiology, presentation and complications of neonatal seizures. To evaluate the clinical, CT scan Brain, EEG, Neurosonogram, metabolic profile and CSF analysis in these babies. To determine the response to antiepileptic drugs and outcome in these babies. Material and methods: Study was done at Neonatal intensive care unit and nursery of a” Tertiary Care Teaching Hospital, Central Andhra Pradesh, South India”. Study Group comprised of 108 neonates with neonatal seizures admitted over the period of one year were included in the study. Both term and preterm babies were included. Results: Out of the 108 neonates in the study 58 were female 50 were male. 74 were born at term (39 male and 35 female). 34 babies were delivered prematurely. (18male, 16female). Out of 74 cases of term babies, normal outcome was observed in 30 cases (40.5%), sequelae have been observed in 26 cases (35.1%), 13 cases expired (17.6%).Out of 34 cases of preterm babies, 13 cases had normal outcome (38.2%), death occurred in 12 cases (35.3%), sequelae have been observed in 8 cases (23.5%). Conclusion: Neonatal seizures are a common cause of neonatal morbidity and mortality. The most common cause of neonatal seizures are perinatal asphyxia and neonatal sepsis. CT Scan Brain and Neurosonogram are useful in early detection of cerebral edema, ischemic hypo densities and haemorrhages which have an important prognostic significance.
Authors and Affiliations
D. Srinivasa Rao, B. Deeva Kumar
Keywords
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