A Study on Effects of TSH Suppression Therapy in Hypothyroidism

Journal Title: International Physiology - Year 2017, Vol 5, Issue 2

Abstract

Background: Thyroid disease is one of the most common endocrine problems managed by general physicians in the endocrinology practice. Hypothyroidism as a clinical syndrome was recognized even later than hyperthyroidism and at first its cause was equally obscure. Common causes of Hypothyroidism are Iodine deficiency, Auto immunity like Atrophic Thyroiditis, Hashimoto’s thyroiditis, Drug Induced Hypothyroidism. Methods: The study comprised of 40 subjects, classified into 2 groups each, with 20 subjects. Group I – 20 (Healthy individuals) controls aged between 20–45 years with euthyroid status. Group II20 Hypothyroid subjects with suppressed levels of TSH aged between 20 to 45 years. The parameter like T3, T4, TSH, Ca+2, Po4 3, ALP, PTH and 25OH VitDmeasured. Results: The mean value of TSH was 2.42±1.08 in controls and 0.15±0.00 was in hypothyroid treated, the mean value of T4 was 98.45±21.92 in controls and 139.65±37.90 was in hypothyroid treated, the mean value of T3 was 1.25±0.33 in controls and1.36±0.48 was in hypothyroid treated.The mean value of mean bone mineral area in lumbar spine, femur neck and radius & ulna were 47.53±3.80, 4.47±0.35 and 4.50±0.45 respectively. The mean value of bone mineral area in lumbar spine is less compared to controls. Themean values bone mineral density of lumbar spine, femur neck, and radius & ulna were 39.47+5.07, 3.23+0.54 and 2.89+0.43 respectively. Conclusion: The patients on long term treatment of drugs likelevothyroxine, in spite of treating hypothyroidism there is aloss of bone mineral density although not with a higherfracture rate due to suppression of TSH levels.

Authors and Affiliations

Ashwini S. a

Keywords

Related Articles

A Study of Perceived Stress Levels in First Year Medical Students in South India

Introduction: Medical students during their course of education may experience stress when their curricular demands tends to exceed their resources to deal with them, and they have been also reported to suffer from highe...

Study of Anthropometric Parameters as Predictors of Diabetes Mellitus

Introduction: Diabetes is a group of metabolic disorders in which there is high blood sugar level over a prolonged period and which leads to many complications such as cardiovascular disease, neuropathy, nephropathy, ret...

A Study of Autonomic Function Tests in Undergraduate Medical Students

Context: Among undergraduate medical students, the relation between mood disturbances associated with the psychological or physical stressors induced by studying and the medical training and the modifications of ANS has...

Effect of BMI on Visual Reaction Time in School Bus Drivers

The present study was carried out in the Department of Physiology, MGM Medical College, Indore. Type of study: cross-sectional study. Sample size: 100 School bus drivers. Age group: 20 to 50years, males. To find out the...

Effect of Meditation on Cardiovascular and Respiratory Parameters

Aim: The aim of present study was to study the effect of Anapanasati meditation on cardiovascular and respiratory parameters among short term meditators (practicing meditation for less than 6 months), long term meditator...

Download PDF file
  • EP ID EP461922
  • DOI 10.21088/ip.2347.1506.5217.11
  • Views 104
  • Downloads 0

How To Cite

Ashwini S. a (2017). A Study on Effects of TSH Suppression Therapy in Hypothyroidism. International Physiology, 5(2), 101-106. https://europub.co.uk/articles/-A-461922