A Study on Effects of TSH Suppression Therapy in Hypothyroidism
Journal Title: International Physiology - Year 2017, Vol 5, Issue 2
Abstract
Background: Thyroid disease is one of the most common endocrine problems managed by general physicians in the endocrinology practice. Hypothyroidism as a clinical syndrome was recognized even later than hyperthyroidism and at first its cause was equally obscure. Common causes of Hypothyroidism are Iodine deficiency, Auto immunity like Atrophic Thyroiditis, Hashimoto’s thyroiditis, Drug Induced Hypothyroidism. Methods: The study comprised of 40 subjects, classified into 2 groups each, with 20 subjects. Group I – 20 (Healthy individuals) controls aged between 20–45 years with euthyroid status. Group II20 Hypothyroid subjects with suppressed levels of TSH aged between 20 to 45 years. The parameter like T3, T4, TSH, Ca+2, Po4 3, ALP, PTH and 25OH VitDmeasured. Results: The mean value of TSH was 2.42±1.08 in controls and 0.15±0.00 was in hypothyroid treated, the mean value of T4 was 98.45±21.92 in controls and 139.65±37.90 was in hypothyroid treated, the mean value of T3 was 1.25±0.33 in controls and1.36±0.48 was in hypothyroid treated.The mean value of mean bone mineral area in lumbar spine, femur neck and radius & ulna were 47.53±3.80, 4.47±0.35 and 4.50±0.45 respectively. The mean value of bone mineral area in lumbar spine is less compared to controls. Themean values bone mineral density of lumbar spine, femur neck, and radius & ulna were 39.47+5.07, 3.23+0.54 and 2.89+0.43 respectively. Conclusion: The patients on long term treatment of drugs likelevothyroxine, in spite of treating hypothyroidism there is aloss of bone mineral density although not with a higherfracture rate due to suppression of TSH levels.
Authors and Affiliations
Ashwini S. a
Keywords
Related Articles
- EP ID EP461922
- DOI 10.21088/ip.2347.1506.5217.11
- Views 56
- Downloads 0
Comparative Study of Event Related Potential in Athletes and Healthy Adults
Background: Cognitive Evoked Potential components are depend on mental attention of subject which are related with cognition, memory. Aims and Objectives: The purpose of study is comparison of properties of event related...
A Correlative Study of Body Composition and Lipid Profile in Postmenopausal Women
Introduction: Cardiovascular disease is a leading cause of mortality in men and women in industrialized world.As Indian population differs in body composition and lifestyle, this study was undertaken to correlate the bod...
HRV in Wards of Hypertensive Parents During Deep Breathing
Background: Hypertension is one of the most rampant diseases in the world. Many genes are responsible for expression of normal blood pressure. This hints a probable role of family history in the development of hypertensi...
A Comparative Study of Mean Visual Reaction time for Red Color in School Bus Drivers with Normal Population (Controls)
Background: Reaction time is the speed with which an individual can respond to a stimulus. Reaction time is very important aspect in occupation like driving, in which quicker level of response is one of the measure by wh...
A Randomized Control Study on Effect of 12 Weeks Yoga Therapy in Type 2 Diabetes Mellitus Patients with Distal Polyneuropathy
Background: Yoga asana practices were documented for therapeutic use in diabetes mellitus Type 2 patients. The progress and complications of diabetes could be reduce by prescribing yoga therapy. Material and Method: The...