A Study on Medical Management in End Stage Renal Disease In Patient on Haemodialysis
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2018, Vol 13, Issue 4
Abstract
End –stage renal disease (ESRD) is the final stage of chronic kidney disease in which the kidney no longer function well enough to meet the needs of dailylife. Based on this, a Prospective Observational study was performedin Department of Medicine, at RMMCH, Annamalai University, TamilNadu, period of study 6 months; Between November 2016 and April 2017. Totally 54 patients were enrolled based on the inclusion and exclusion criteria.The patients were counseled about their disease and lifestyle modification. The objective of the study is to find out the socio-demographic characteristics of ESRD patients, to observe the variation in blood pressure before and after hemodialysis, anemic condition in hemodialysis patient and to study the drug use pattern in ESRD patients at RMMCH. In our study we observed that males are majorly affected with ESRD and the patients of age group of 30-40 years are mostly affected than other age group.The working status of the patients enrolled in our study was mostly daily wagers and farmers. In male the risk factor of alcohol consumption is mostly noticed. By observing both pre and post dialysis data we could be noticed that there is an increase in blood pressure after dialysis, but in few patients we also observed that decrease in BP after dialysis. In our study the mean of the haemoglobin level is low as compared with the target range recommended by the KDOQI guidelines and they are treated with injection iron sucrose and erythropoietin to increase the Hgb level. Blood transfusions are given only to the patients with very poor haemoglobin level. Among all the antihypertensive drugs prescribed amlodipine (calcium channel blocker) was majorly prescribed drug, followed by (cardioselective beta blocker). Combination of diuretic and calcium channel blockers was commonly prescribed in DM with HT patients. From our study we conclude that monotherapy is preferred for the haemodialysis patients on long term use of antihypertensive drugs for the better control of blood pressure.
Authors and Affiliations
Likitha Nanga, Geena Gimson, G. Veeramani, ,Dr . K. Baburaj
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