A Study on the Clinical and Laboratory Profile of Patients Having Thrombocytopenia in Pediatrics
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2018, Vol 6, Issue 7
Abstract
Introduction: Fever is a symptom which is caused by a variety of illnesses and it usually occurs in response to an infection or inflammation. Patients presenting with fever in tropical country like India usually have an infectious etiology, and many have associated thrombocytopenia. Aim: This study aims to assess the clinical and laboratory profile of patients having thrombocytopenia (<1 lakh) in pediatrics. Materials and Methods: The patients of both sexes aged 2 months–12 years. Patients with platelet count <1 lakh at during the course of hospital stay, irrespective of the cause for admission were included. Data regarding the patient were entered into preset pro forma as regard to the history, general and systemic examination, Hess test, and vital signs. The bleeding manifestation’s patients presented with or developed during their course in hospital were recorded. Results: The most common age group of presentation of thrombocytopenia among the study group is 6–10 years, constituting 47.3% of the cases. Mortality is highest among infants. The most common etiology for newly diagnosed thrombocytopenia among children admitted is dengue. The most common presenting symptom among the study group is fever (95.5%) with vomiting being the second most common symptom (65.2%). 76.1% of children with vomiting had bleeding manifestations. In children with thrombocytopenia, the presence of altered sensorium, tachycardia, tachypnea, shock at presentation, and seizures was all significantly associated with low platelet counts, bleeding, and mortality. Conclusion: Febrile thrombocytopenia is a commonly observed hematological entity commonly caused by infections such as viral illnesses, dengue, malaria, and enteric fever. Dengue shock syndrome is the leading cause of mortality in the present study.
Authors and Affiliations
L Venkatraman, C Baskar, Heber Anandan
Keywords
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