A Study Onclinical Profile of Stroke in Very Elderly
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 10
Abstract
Background:The incidence of stroke and level of poor outcome after stroke (in terms of disability and mortality rate) both increase with age. With the growth of the global elderly population, the prevalence of stroke will also rise. Objective of the study: To examine demographic characteristics, clinical features, neuroimaging data, andoutcome of all first ever stroke events occurring in individuals aged 75 years or older. Methods:This is a retrospective study of all first ever437 stroke patients referred to neurology department over 1-year. Data iscollected from hospital-based stroke registry.For the purpose of this study, very old patients (aged 75 years or older) were selected (n = 100). The data of very old stroke patients were compared withthe data of patients younger than 75 years of age (n = 337). The data is analysed using SPSS version 21.0. Results: Mean ages and sex ratios (women/men) were 79.7±5.2 and 61.4±11.4 years and 1.63 and 0.71 for the older and younger groups, respectively. Elderlypatients showed a significantly lower proportion of diabetes (17% versus 30.8%) and smoking (3% versus 15.5%) and a higher proportion of peripheral artery disease (16% versus 6.8%) and atrial fibrillation (17% versus 6.8%). Hypertension was the commonest risk factor in the 2 groups. There were no significant differences in ischemicstroke subtypes between the 2 groups.Acute stroke in the very old patients was more severe than in patients younger than 75 years of age, with greater rates of in-hospital mortality (22% vs. 12.6%, ), longer duration of hospital stay (14.8±9.2 vs. 9.2±7.2 days), and lesser frequency of absence of neurologic deficit at the time of hospital discharge (15.5% vs. 26.2%). Conclusion: Very old patients with acute stroke showed a differential clinical profile, differentfrequency of risk factors, and a poorer outcome compared with stroke patients who wereyounger than 75 years of age. Clinical and neuroimaging factors that are indicative of the severityof stroke and that were available at the time of the initial diagnosis and at the time of thedevelopment of cardiac and respiratory complications showed a predominant influence on in-hospitalmortality and may help clinicians to establish prognosis more accurately
Authors and Affiliations
Murugapandian Nagarajan, Arunan Subbiah, Palani Kannan
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