A Study to Assess the Ocular Biometric Parameters and Prevalence of Refractive Errors among Thalassemic Children in a Rural Based Tertiary Hospital
Journal Title: International Journal of Health Sciences and Research - Year 2017, Vol 7, Issue 4
Abstract
Introduction: Thalassaemia major patients have characteristic skeletal changes, including typical craniofacial changes and deformities of the long bones that result from expansion of the bone marrow. Craniofacial changes in thalassaemia major patients might lead to an abnormal bony orbit and subsequently might lead to distinctive ocular biometry and/or refraction. Materials and Methods: 523 Thalassemic children and 502 age and sex matched control population were selected by systematic random sampling. Comprehensive ophthalmological examination was done on both case and control groups. The obtained data has been analysed by standard statistical software. Results and Analysis: The Thalassemic children had lower mean weight than the control group (p<0.00, t=99.0, SED: 0.17, 95%CI:-16.72 to -16.07). The mean axial length of the eyeball was less among the Thalassemic children (p=0.04, t=2.00, SED: 0.10, 95% CI:-0.40 to 0.00). The average lenticular thickness was comparatively more among Thalassemic Children (p=<0.00, 10.64, SED:0.00, 95%CI: 0.05 to 0.08). The average keratometry value was lower among the Thalassemia children (p=0.04, t=2.08, SED: 0.10, 95%CI: -0.39 to -0.01). Astigmatism was more among the Thalassemic children (p=0.04, z=2.06). Conclusion: Due to differential phenotypic expressions Thalassemic children may have abnormal ocular biometric characteristics.
Authors and Affiliations
Dr. Arunava Kundu
Keywords
Related Articles
- EP ID EP369331
- DOI -
- Views 79
- Downloads 0
Case Reports on Tooth-Supported Overdenture
Instead of extraction, a clinician can preserve and utilise the remaining teeth of a nearly edentulous patient as abutments for an overdenture. Overdenture can be described as any removable dental prosthesis that covers...
Health Warning Labels on Tobacco Products: A Review
Tobacco is the most common cause of preventable death in the world. Majority of people are unaware of, misunderstand or underestimate the health risks due to tobacco and tobacco smoke. Health warnings were first introduc...
Effect of Crude Extract of Khat (Catha Edulis) On the Plasma Glucose Level of Normoglycemic and STZ Induced Type 2 Diabetic Rats
Khat is chewed traditionally in Ethiopia, Somalia, Yemen and Kenya. In Ethiopia, khat chewing is now becoming an everyday substance of abuse for the general population. Clearly, knowledge about the effects of cathinone a...
Poverty: What is it and what is it not? A concept analysis
Objectives: There is no single “correct” definition of poverty. However, there is consensus that any definition of poverty needs to acknowledge particular social, economic and cultural contexts. Different meanings of pov...
Awareness and Practice of Mother Having Under Five Children Regarding Prevention of Childhood Accident
Injuries are the first leading but predictable, avoidable and preventable cause of morbidity and mortality among under five-year children worldwide. A descriptive cross-sectional study aimed to find out Awareness & Pract...