A Study to Compare Effects of Magnesium Sulphate and Fentanyl with Bupivacaine for Postoperative Analgesia in Perianal Surgeries
Journal Title: Indian Journal of Anesthesia and Analgesia - Year 2019, Vol 6, Issue 2
Abstract
Context: Magnesium prolongs analgesia in humans when given intrathecally. Fentanyl being highly lipid soluble diffuses into spinal cord and binds to dorsal horn receptors rapidly when administered intrathecally.Aims: To compare the effects of magnesium sulphate and fentanyl with bupivacaine for post operative analgesia in perianal surgeries. Material and methods: 42 patients aged 18-65 years of ASA Grade I and II scheduled for perianal elective surgeries under spinal anaesthesia were allocated equally in two groups according to chit system randomly. Group BF- Inj. bupivacaine 0.5% 1 ml+25 µg fentanyl (preservative free) 0.5 ml. Group BM- Inj. bupivacaine 0.5% 1 ml+100 mg magnesium sulfate (preservative free) diluted to 0.5 ml with normal saline. Patients were observed for onset and duration of sensory and motor blockade, duration of postoperative analgesia and analgesic requirement in first 24 hours. Statistical analysis: The statistical analysis was assessed by unpaired t-test on Microsoft excel and IBM SPSS version 21. Results: Duration of sensory block, motor block and postoperative analgesia was significantly more in BM group than in BF group (p<0.001). Time to rescue analgesia in group BF was significantly less than that in group BM (p<0.001). Conclusion: Though the onset of motor and sensory block is delayed with intrathecal magnesium sulfate, duration of analgesia is prolonged as compared to intrathecal fentanyl. Total analgesic requirement is significantly more with fentanyl as compared to magnesium.
Authors and Affiliations
Sakshi Yadav
Keywords
Related Articles
- EP ID EP619100
- DOI 10.21088/ijaa.2349.8471.6219.17
- Views 55
- Downloads 0
Evaluation of Propofol with Propofol -Midazolam for I-gel Insertion in Impulsively Breathing Patients for Elective Day Care Procedures
Background and Aim: The I-gel is the innovative second generation supraglottic airway device from Intersurgical. I-gel offers unique advantages of easy insertion, reduced trauma, superior sealing pressure, and gastric ac...
Oral Premedication in Paediatric Surgeries under General Anaesthesia with Ketamine versus Midazolam: A Comparative Study
Background: Pre-operative anxiety (anxiety regarding impending surgical experience) in children is a common phenomenon that has been associated with a number of negative behaviors during the surgical experience (e.g. agi...
Ultrasound Guided Combined Superficial Cervical Plexus BlockInterscalene Block for Anesthesia in Clavicular Fractures: A Retrospective Observational Cohort Study
Background: Even though various peripheral nerve blocks are used for analgesia in clavicular fractures. The use of ultrasound guided combined superficial cervical plexus block and interscalene blocks as a sole anaestheti...
Comparison of Preemptive Intraperitoneal Instillation and Nebulisation of 0.5% Ropivacaine in Laparoscopic Cholecystectomy for Post-operative Pain Relief
Objective: The etiology of postoperative pain in patients undergoing laproscopic cholecystectomy is multifactorial consisting of incisional and visceral pain from the operation itself and parietal pain from trauma and ir...
Comparison of the Efficacy of Palonosetron and Ondansetron in Prevention of Postoperative Nausea and Vomiting
Background and objectives: Post-operative nausea and vomiting (PONV) is commonly seen in female patients undergoing laparoscopic surgeries under general anaesthesia. Adverse consequences of PONV are patient dissatisfacti...