A Study To Compare The Effects Of Low Dose Intrathecal Fentanyl And Low Dose Intrathecal Tramadol Combined With 0.5% Bupivacaine (Heavy) In Patients Undergoing Lower Limb Surgeries”
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 11
Abstract
Introduction: Intrathecal opoids are used as adjuvants in spinal anaesthesia to increase the duration and quality of anaesthesia.The present study was designed to quantitatively examine the safety and efficacy of fenatnyl and tramadol to hyperbaric bupivacaine for spinal anaesthesia in lower limb surgeries Materials and Methods: Sixty patients undergoing elective lower limb surgeries under spinal anaesthesia at our hospital were chosen for the study during the period January 2015 and September 2016. Patients were randomly allocated into two groups of 30 each. Both groups compared for sensory and motor blockade characteristics. Statistical analysis was performed using statistical package for social sciences (SPSS) for Windows version 16.0 software, Chicago, SPSS Inc. Results: Demographic parameters like age, sex, and ratio of ASA were comparable between the study groups. The mean time to reach T10 sensory block level in group F and group T were 3.14±0.69 and 3.16±0.65 respectively, the time to reach peak sensory block level were 9.14±1.22 min and 8.94±0.87 min in group F and group T, time for two segment regression of sensory level in group F and group T were 98.13±8.01 min and 100.76±8.601 min (p=0.9084, 0.4677, 0.2253 respectively). The time of onset of Bromage 3 motor block were 9.33±1.13min and 9.45±1.19 min in group F and group T and time to regression to Bromage 0 motor block in group F and group T were 237.46±8.20 min and 235.33±12.98 min(p=0.69,0.45 respectively). The mean duration of analgesia in group F was 423.26±12.83 and the mean duration of analgesia in group T was 351.7±20.78 which was statistically significant (p=<0.0001). Conclusion: The present study showed that the sensory blockade and motor blockade characteristics were similar with fentanyl and tramadol when added to hyperbaric bupivacaine but the duration of analgesia was significantly higher with lower visual analogue scale scores in fentanyl group compared to tramadol group.
Authors and Affiliations
Sindhu Talluri, Kalyan Rakam
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