A Survey Determining the Different Genotypes of Hepatitis C Amongst Subjects Reporting to a Tertiary Care Centre in Punjab
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 1
Abstract
Background: HCV poses a challenge to the improvement in the development of vaccines and pan-genotypic treatments, which require the consideration of global trends in HCV genotype prevalence. Therefore, the development of national treatment strategies using DAA therapies requires a detailed understanding of relative HCV genotype prevalence and subtypes. The aim of the present study is to determine different Genotypes of Hepatitis C Amongst Subjects Reporting to a Tertiary Care Centre in Punjab. Materials and Methods: The present study included 437 subjects with hepatitis C reporting to the Medicine department, GMC Patiala. The genotypes obtained were matched with the chart obtained by the manufacturer. All the results obtained were arranged in the tabulated form and analysed using SPSS software. Results: Out of total 292 non cirrhotic patients Genotype 3 was found to be most prevalent in 125 patients (42.8%), followed by genotype 1 in107 patients (36.6%) and genotype 4 in 58 patients (19.8%). There were 73 males and 52 females amongst genotype 3, and 71 males and 36 females with genotype 1. There was 1 male with genotype 2. There was 1 male with genotype 5. Out of total 145 cirrhotic patients; 40 (27.6%) patients had genotype 1, and 84 (57.9%) had genotype 3, 20 (13.8%) had genotype 4, and 1 (0.68%) genotype 5. Conclusion: In the above study genotype 3 was most prevalent amongst patients with hepatitis C. Genotype 1 was the second most common type.
Authors and Affiliations
Sanjay Goyal, Satish Sachdeva, Gurpreet Singh, Rajiv Aggarwal, Simratjit Kaur
Keywords
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- EP ID EP530014
- DOI 10.21276/ijmrp.2018.4.1.057
- Views 87
- Downloads 0
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