A Systematic Review for the Contraceptive Efficacy and Safety of Compound Left Acetylene Progesterone Tablets from 2-amino-1,4-naphthoquinones.
Journal Title: Journal of Pharmaceutical and Biomedical Sciences - Year 2016, Vol 6, Issue 6
Abstract
Background and Objectives There is limited information on the efficacy and safety of compound left acetylene progesterone tablets (LNG/EE 100/20 μg) in contraception. To evaluate the efficacy and safety of LNG/EE 100/20 μg for contraception. Method We searched the medical databases including Pubmed, Web of science, EMbase and Cochrane library through computer; extracted and evaluated the data then performed the meta-analysis by using Review Manager 5.3 software. Result A total of seven randomised controlled trials including 1786 subjects were recruited for meta-analysis. Compared with other compound oral contraceptives, LNG/EE 100/20 μg showed no significant differences in contraception efficacy [OR = 1.08, 95% CI (0.29, 4.04), P = 0.91] and safety [OR = 0.99, 95% CI (0.81, 1.21), P = 0.92]; however, it is better than the other compound oral contraceptives on cycle control efficacy of short cycle [OR = 1.75, 95% CI (1.28, 2.38), P = 0.0004]. Conclusion LNG/EE 100/20 μg were better than the other compound oral contraceptives on cycle control of short cycle, and showed no significant differences in the efficacy and safety.
Authors and Affiliations
Guo-hua Cheng, Min Yang, S-Shan Zhou, Y-Zhen Zhang
Keywords
Related Articles
- EP ID EP183489
- DOI -
- Views 74
- Downloads 0
Vascular Thoracic Fibrous Adipose Tissue (New Disease)
Indroduction The primary tumors of the chest wall are rare, about 2% of all cancers, and 50% are derived from soft tissue neoplasms, benign or malignant that arise at the level of the chest wall representing 2% of all ca...
Revisiting the Utility of Biochemical Profile in the Diagnosis and Management of Hepatitis C Virus Infection: a Study from India
Several serum analytes can be used for the management of liver diseases. The present study was carried out to assess the role of biochemical markers in the diagnosis and prognosis of HCV infection. Blood samples (5 ml) c...
Fufang Danshen Pian (Danshen Tablets) Ameliorates Myocardial Infarction Injury via Endothelial Protection in Rats
Objective Compound Danshen Tablets (CDT), also known as Fufang Danshen Pian in China, has been commonly used to prevent and treat cardiovascular diseases in the clinic in Asia-Pacific region, especially in China. This st...
Oral Misoprostol Versus Intravenous Methylergometrine for the Prevention of Postpartum Haemorrhage
Background Post partum haemorrhage is one of the most common causes of maternal mortality. Uterine atonicity, trauma to the genital tract, retained product of placenta are common causes of postpartum haemorrhage (PPH), o...
A Study on Budesonide/ Formoterol vs. Fluticasone/ Salmeterol Inhaled Combination in Moderate to Severe Asthma
Background and Objectives The addition of an inhaled long-acting β2-agonist (LABA) to an inhaled corticosteroid (ICS) gives optimal control of asthma in most patients. The LABA salmeterol xinafoate (salmeterol) with inha...