Oral Misoprostol Versus Intravenous Methylergometrine for the Prevention of Postpartum Haemorrhage
Journal Title: Journal of Pharmaceutical and Biomedical Sciences - Year 2016, Vol 6, Issue 6
Abstract
Background Post partum haemorrhage is one of the most common causes of maternal mortality. Uterine atonicity, trauma to the genital tract, retained product of placenta are common causes of postpartum haemorrhage (PPH), out of these, atonicity contributes to a majority of cases. Many drugs have been used for the contraction of the uterus such as oxytocin, misoprostol and methylergometrine. In this study, the role of IV methylergometrine was compared with oral misoprostol for the prevention of PPH. Materials and Methods Study of 180 women who received IV methylergometrine or oral misoprostol 600 mcg to prevent post PPH was carried out in the labour room of Hi-Tech Medical College and Hospitals, Bhubaneswar, Odisha, India, between January 2014 and January 2015. Result In this study oral misoprostol was found to be safe, non invasive and effective method in prevention of PPH specially in low resource setting in India. Conclusions In this study oral misoprostol was found to be safe, non invasive and effective method in prevention of PPH specially in low resource setting in India.
Authors and Affiliations
Amit Agrawal, Pratima Mishra
Keywords
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