A SYSTEMATIC REVIEW ON THE SYNTHESIS AND BIOLOGICAL ACTIVITY OF HYDRAZIDE DERIVATIVES
Journal Title: Hygeia:journal for drugs and medicines - Year 2017, Vol 9, Issue 1
Abstract
Plan:A systematic reviewon the synthesis and biological activity of hydrazides and their derivatives. Preface: The chemistry of hydrazide and its derivatives has obtained great interest in both organic chemistry and biological science with remarkable impact. The development of novel organic compounds with antimicrobial, antiviral, anti-inflammatory, anti-tubercular, antibacterial, antifungal activities have been of great interest and pharmaceutical importance. Hydrazides andhydrazonesare possessing an NHNH2 and NHN=CH- groups respectively. The availability of proton in hydrazides constitutes them as an important class of compound for new drug discovery. Therefore, researchers have showed great interest in developing these compounds as target structures for evaluating new biological activities. Outcome:This review emphasizeson various methods ofsynthesis and several biological activities possessed by hydrazide and hydrazone derivatives, which may helpthe researchers for the design and development of novel hydrazides as potential candidate in pharmaceutical science.
Authors and Affiliations
Mohd. Shahnawaz Khan, Saba Parveen Siddiqui, Nazia Tarannum
Keywords
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- EP ID EP332919
- DOI 10.15254/H.J.D.Med.9.2017.165
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