A Translocation Renal Cell Carcinoma with Skeletal Muscle Metastasis in a Child
Journal Title: Turkish Journal of Pathology - Year 2017, Vol 33, Issue 3
Abstract
Renal cell carcinoma is a tumor that is well known for a high rate of metastasis to several locations like the lung, liver and bones. Skeletal muscle is a rare location for dissemination of the disease. Herein, we describe a 7-year-old boy who presented with flank pain. On physical examination, an abdominal mass located on the left kidney as well as a solid palpable lesion on the left upper arm were detected. Total nephrectomy with subsequent excision of the arm mass was performed. Pathology examination revealed presence of translocation renal cell carcinoma. The patient received α-interferon followed by multikinase inhibitor (Sorafenib) treatment but was lost due to progressive disease. This is the first description of a pediatric patient with skeletal muscle metastases of translocation renal cell carcinoma in the literature.
Authors and Affiliations
Gülen TÜYSÜZ, Nihal ÖZDEMİR, Haluk EMİR, Haydar DURAK, Sergülen DERVİŞOĞLU, İbrahim ADALETLİ, Hilmi APAK
Keywords
Related Articles
- EP ID EP255227
- DOI 10.5146/tjpath.2014.01259
- Views 46
- Downloads 0
Phyllodes Tumor of Anogenital Mammary-like Glands with Diffuse Pseudoangiomatous Stromal Hyperplasia
Anogenital mammary-like glands may give rise to various pathologic lesions identical to those known in mammary pathology. Tumor occurring in the anogenital region is extremely rare. The histogenetic origin of this tumor...
The World Health Organization Classification of Odontogenic Lesions: A Summary of the Changes of the 2017 (4th) Edition
The 4th edition of the World Health Organization (WHO) Classification of Head and Neck Tumors was published in January 2017. The edition serves to provide an updated classification scheme, and extended genetic and molecu...
Angiocentric Glioma: The Infiltrative Glioma with Ependymal Differentiation
Angiocentric glioma is an epileptogenic, infiltrative, low grade glial tumor, with ependymal and astrocytic differentiation, most commonly seen in young adults and the pediatric age group. Herein we report a case of 21-y...
Intra-Articular Glomus Tumor– A Rare Presentation
-
Lhermitte-Duclos Disease: A Rare Lesion with Variable Presentations and Obscure Histopathology
Since Lhermitte-Duclos is a quite rare disorder with both neoplastic and hamartomatous features, clinical and pathological diagnosis can sometimes be challenging. For the pathologist it is of extreme importance to be awa...