Acquired Antimicrobial Resistance Genes of Escherichia coli Obtained from Nigeria: In silico Genome Analysis
Journal Title: Journal of Food Quality and Hazards Control - Year 2021, Vol 8, Issue 4
Abstract
Background: Antimicrobial resistance is a global problem with enormous public health and economic impact. This study was carried out to get an overview of acquired antimicrobial resistance gene sequences in the genomes of Escherichia coli isolated from different food sources and the environment in Nigeria. Methods: To determine the acquired antimicrobial-resistant genes prevalence, genome assemblies of 272 isolates were analyzed In silico with KmerResistance 2.2 software. Results: A total of 107 antimicrobial resistance genes, which included genes that encode for 24 extended-spectrum beta-lactamases were detected. Potential multidrug resistance was found in 90% of the genomes analyzed. All strains analyzed contained at least one resistant gene sequence and had high similarity or homology (95% ID and above). Two strains harboured over 30 sequences of antimicrobial resistant genes, and in 24 strains over 20 genes were detected. Conclusion: The resistant genes found in all the genomes analyzed were acquired intra-species and not inter-species. This provides an opportunity for further studies of the orthologous nature of the genes detected and the data obtained can help monitor the epidemiology of E.coli resistant genes in the food and environment. DOI: 10.18502/jfqhc.8.4.8260
Authors and Affiliations
O. Nwaiwu,H. Onyeaka,
Keywords
Related Articles
- EP ID EP699550
- DOI -
- Views 51
- Downloads 0
Physio-chemical and Microbiological Quality Assessment and Detection of Adulterants in Different Sources of Milk in Bangladesh
Background: The sources of milk play a significant role on overall milk quality. Therefore, the current study was intended to evaluate the quality (physiochemical, compositional, and microbiological) and detect the adult...
High Prevalence of Mycotoxigenic Fungi and Aflatoxin B1 Contamination in Corn and Wheat Grains Grown to Albania: Implications for Food Safety
Background: Today, mycotoxins are considered critical contaminants in foodstuffs produced by fungi, highlighting the importance of food safety to human health. The toxigenic fungi invasion and mycotoxin production are hi...
Microbial and Fungal Contamination of Different Dried Cocoyam Flakes during Storage
Background: Contamination of food by microorganisms from the processing to the consumption stage has become a major health concern in this era, where a better approach for the elongation of food shelf life is explored. T...
Benefits and Risks of Aquaculture Foods in Primary Health Care: A Mini-Review
Primary Health Care (PHC) is expected to serve as a basis for the country's health sector, of which it is the primary responsibility and priority, as well as the community's overall collective and economic prosperity. Pr...
Phenotypic and Genotypic Characteristics of Methicillin-Resistant Staphylococcus aureus Isolated from Dairy and Meat Products in Iran
Background: Methicillin-Resistant Staphylococcus aureus (MRSA) plays an important role in gastrointestinal diseases. The goal of this research was to determine phenotypic and genotypic characteristics of MRSA isolated fr...