Acrylamide. Documentation of suggested occupational exposure limits (OELs)
Journal Title: Podstawy i Metody Oceny Środowiska Pracy - Year 2014, Vol 30, Issue 2
Abstract
Acrylamide (AA) is a chemical compound that occurs at room temperature in the form of colorless crystals or flakes. It is not found in the natural environment, but it can be produced in thermal food processes (frying, baking). It is also present in cigarette smoke. Acrylamide is categorized as a toxic substance that poses substantial health risk after long-term exposure via inhalation, ingestion or skin contact. It is a category 2 (1B) mutagen and category 2 (1B) carcinogen. AA is known to induce adverse effects on reproduction, eye irritation and allergic skin reactions. Acryla-mide is produced in multi-tonnage quantities. It is mostly used to synthesize polyacryla-mides applied in wastewater treatment, man-ufacturing paper, processing ore, manufactur-ing vinyl polymers; it is also used as a grouting agent in constructing dams and tunnels. Polyacrylamide gel is utilized in the process of electrophoresis (PAGE) commonly used in numerous laboratories.Occupational exposure to acrylamide may occur during the produc-tion, processing and distribution of this com-pound and also during its application in construction and assembly works (e.g., construction of tunnels, sewer grouting work). In Poland occupational exposure to acrylamide is observed in chemical and pharmaceutical plants as well as in laboratories of research institutes and tertiary education schools. Over 2000 workers (mostly women) were exposed to this compound in the years 2005–2010 (2525 workers in 2010). According to the data produced by the Chief Sanitary Inspectorate in 2011 and 2012 there were no workers exposed to acrylamide at levels exceeding maximum allowable concentration (MAC) in the air, namely over 0.01 mg/m3. <br/><br/>
Authors and Affiliations
Andrzej Sapota, Małgorzata SKRZYPIŃSKA-GAWRYSIAK
Keywords
Related Articles
- EP ID EP224516
- DOI 10.5604/1231868X.1111926
- Views 91
- Downloads 0
Dimethyl phthalate – inhalable fraction. Documentation
Dimethyl phthalate (DMP) is a colorless, oily liquid with a faint aromatic odor.It is used in the chemical industry (manufacture of dyes, varnishes) and cosmetics (perfume, bubble bath, etc.) as a plasticizer (e.g., c...
Docetaksel. Metoda oznaczania w powietrzu na stanowiskach pracy z zastosowaniem wysokosprawnej chromatografii cieczowej
Docetaksel (DCT) to cytostatyk pochodzenia roślinnego z grupy taksoidów – inhibitorów mitozy. Docetaksel jest cytostatykiem stosowanym w leczeniu raka: piersi, płuc, gruczołu krokowego, płaskonabłonkowego głowy i szyi or...
Hydrazine. Determination in workplace air with high performance liquid chromatography – spectrophotometric technique
Anhydrous hydrazine in room temperature is colorless fuming oily liquid with ammonia-like odor. It is used in various industries for electrolytic plating of metals on glass and plastics, as a chemical intermediate for th...
3,3’-Dimetoksybenzydyna. Metoda oznaczania w powietrzu na stanowiskach pracy
3,3’-Dimetoksybenzydyna (DMOB) jest substancją zaklasyfikowaną do grupy substancji rakotwórczych. W Polsce zaproponowano wartość najwyższego dopuszczalnego stężenia (NDS) dla tej substancji na poziomie 0,2 mg/m3. Celem p...
Docetaxel. Determination in workplace air with high performance liquid chromatography
Docetaxel (DCT) is a plant derived cytotoxic from taxane family - mitosis inhibitors. It is used in the treatment of breast, lung and prostate cancer, squamous cell carcinoma of the head and neck, and gastric adenoma. Do...