Activated Nitrogen-Containing Metabolites of the Human Body in Respiratory Diseases. Generators and Generation (Part 2)
Journal Title: Здоров`я дитини - Year 2015, Vol 7, Issue 67
Abstract
This literature review presents current data about the induction and inhibition of the synthesis of nitric oxide (NO) in respiratory diseases. We have discussed in detail the induction of NO generation by cytokines, the regulation of NO generation by Th1- and Th2-lymphocytes. The signal pathways of the main inducers of the inducible or macrophage nitric oxide synthase (iNOS), as well as transcription factors involved in the regulation of iNOS gene activity were shown. The features of NO production were presented depending on local conditions.
Authors and Affiliations
O. Ye. Abaturov, O. P. Volosovets, T. P. Borysova
Keywords
Related Articles
- EP ID EP217507
- DOI -
- Views 62
- Downloads 0
Peculiarities of somatic pathology in children with cerebral palsy (literature review)
Cerebral palsy remains one of the most topical problems of pediatric neurology and causes of childhood disability. This term includes group of syndromes that result from violations of or damage to the central nervous sys...
Angelman Syndrome. Part 1 (Etiology and Pathogenesis)
The paper presents the current understanding of the mechanisms of genetic changes in Angelman syndrome. This article contains the data on the prevalence and the risk of inheritance of different genetic defects in patient...
Angelman Syndrome. Part 3 (Differential Diagnosis and Treatment)
The article discusses the problem of differential diagnosis and treatment of patients with Angelman syndrome (AS). It provides the most common syndromes with similar to AS phenotypes, the main differences between AS-like...
Allelic Polymorphism of enos Gene in Children Who Suffer from Bronchial Asthma, with Eosinophilic and Paucigranulocytic Subtypes of Bronchial Inflammation
The objective of the research was to study the effect of allelic polymorphism of eNOS gene, encoding the activity of endothelial NO-synthase and synthesis of nitrogen monoxide in the airways, on some clinical and paracli...
Possibility of Phytotherapeutic Effect on Vegetative and Psychoemotional State of Adolescents with Autonomic Dysfunction Syndrome
The article presents the results of a study on clinical efficacy and safety of using complex herbal preparation Sedafiton® in schoolchildren aged 15–18 years with autonomic dysfunction syndrome. A positive effect of the...