Features of Clinical and Laboratory Parameters in Children with Arthritis, which Have Increased Antibody Titers to Cyclic Citrullinated Peptide and Modified Citrullinated Vimentin
Journal Title: Здоров`я дитини - Year 2013, Vol 2, Issue 45
Abstract
77 children with inflammatory lesions of the joints have been examined in the study. The characteristics of clinical signs and laboratory parameters in patients with arthritis, who have increased antibody titers to cyclic citrullinated peptide (a-CCP) and modified citrullinated vimentin (a-MCV) are presented. The patients with juvenile rheumatoid arthritis which a-CCP positive were adolescents, they had polyarticular lesions, a significant number of active joints, and the trend to more rapid development of radiologic stage III by Steinbrocker. Positivity for a-MCV was often detected from an early age, but not only in patients with juvenile rheumatoid arthritis. These patients were seronegative for rheumatoid factor, high frequency of involvement of the knee joints with their swelling. Radiological changes in joints of these patients seldom exceeded II stage by Steinbrocker.
Authors and Affiliations
I. S. Lebets, N. O. Panko
Keywords
Related Articles
- EP ID EP233436
- DOI -
- Views 84
- Downloads 0
Correction of gut microbiota in the treatment of irritable bowel syndrome in children
The purpose of the work was to determine the possibilities of gut microbiota correction in the treatment of children with irritable bowel syndrome according to the analysis of scientific publications 2016–2018 in journal...
State on Colon Motility and Tone of the Intestinal Wall in Chronic Non-Ulcerative Colitis in Children
The article deals with violations of the motor-evacuation function of the digestive tract, presented data on the frequency of functional disorders of motility in chronic colitis in children by the results of electromyogr...
The Role of Endogenous Antimicrobial Peptides in the Bacterial Colonization of the Nasopharynx in Children with Hyperplasia of the Pharyngeal Tonsil
We have investigated the level of antimicrobial peptides in the blood serum of 35 children with adenoiditis associated with hyperplasia of the pharyngeal tonsil. It was found that children with hyperplasia of the pharyng...
Bullous Emphysema Complicated by Spontaneous Pneumothorax Case Study
The article describes the modern view on the formation of the cause and clinical manifestations of bullous emphysema complicated by spontaneous pneumothorax in children. We described a clinical case of intermittent recur...
Cow’s milk protein allergy or lactose intolerance? Principles of differential diagnosis and diet therapy
Clinical gastrointestinal manifestations of cow’s milk protein allergy and lactase deficiency such as diarrhea, bloating, colic, and regurgitation are quite similar, which often lead to errors in diagnoses and methods of...