ACTIVITY OF THE ENZYMES OF THE CARBOHYDRATE METABOLISM IN MUSCLE TISSUE OF RATS WITH EXPERIMENTAL DIABETES FOR THE COMPLEX ACTION OF MAGNESIUM AND CHROMIUN CITRATES
Journal Title: Naukovyi visnyk Chernivetskoho universytetu. Biolohiia (Biolohichni systemy) - Year 2017, Vol 9, Issue 1
Abstract
The aim of our research was to investigate the complex action of magnesium citrate (in the dose of 250 mg Mg2+/kg b.w.) and chromium citrate (in doses of 25 μg Cr2+/kg b.w. and 10 μg Cr2+/kg b.w.) on the functional state of the key enzyme of the carbohydrate metabolism in muscule tissue of rats with experimental diabetes. It was observed that the activity of the glucose-6-phosphate dehydrogenase decreased under conditions of experimental diabetes, but activity of the lactate dehydrogenase increased. At the same time, it was observed decreasing in the content of the pyruvate and increasing in the L-lactate in the muscle tissue of animals with experimental diabetes. It was determined, that the complex of magnesium and chromium citrate, which was added to the diet of the rats, caused the increasing in the activity of glucose-6-phosphate dehydrogenase and the content of the pyruvate, and also increasing in the activity of lactate dehydrogenase and the content of the L-lactate in the muscle tissue.
Authors and Affiliations
О. А. ШАТИНСЬКА, Р. Я. ІСКРА, О. З. СВАРЧЕВСЬКА
Keywords
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