ACUTE FATTY LIVER OF PREGNANCY MASQUERADING AS HELLP SYNDROME
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2018, Vol 5, Issue 19
Abstract
PRESENTATION OF THE CASE A 28-year-old woman, G2P1L1 at 34-weeks gestation was admitted to our hospital with a history of generalized pruritus for 2 weeks. She also complained of malaise, nausea, vomiting, and yellow coloured urine since last ten days. There was no history of fever. She had no respiratory/urinary/neurological complaints. Antenatal history was uneventful. She had no documented evidence of systemic hypertension. Supportive treatment for acute viral hepatitis was given at a private clinic and she was referred to us for further care. Physical examination revealed a well-nourished, somnolent, but easily arousable woman. Her temperature was 36.7°C, pulse rate was 104/min, respiratory rate 20/ min, and blood pressure 120/80 mmHg. She was oriented to person, place, and time, and her focal neurological findings were non-contributory. She was icteric, with mild edema of the legs. Abdomen was no tender. Complete blood counts revealed a haemoglobin: 11g/ dl, total leucocyte count: 10, 400/cumm, and platelet count: 96, 000/cumm. Peripheral smear did not show haemolysis and serum lactate dehydrogenase (S.LDH) levels was high/ Liver function tests showed aspartate aminotransferase: 208 U/l, alanine aminotransferase: 304 U/l, total bilirubin: 18.3 mg/dl, direct bilirubin: 12.7 mg/dl, alkaline phosphatase: 532 U/l, total protein: 6g/dl, and albumin: 2.6 g/dl. Biochemical tests revealed blood urea: 40 mg/dl, serum creatinine: 2.5 mg/dl, serum glucose: 60 mg/dl, and serum ammonia: 106 μmol/L. Coagullogram revealed a prothrombin time of 60 seconds with international normalized ratio (INR) of 3.2, fibrinogen: 62 mg/dl, and fibrin degradation products (FDP): 360 μg/ml. Urine analysis showed mild proteinuria. Serology tests like HBsAg, HCV, and HIV were all negative.
Authors and Affiliations
Santhosh Narayanan, Divya Prakash, Gomathy Subramaniam, Lakshminarayanan Lakshminarayanan
Keywords
Related Articles
- EP ID EP557444
- DOI 10.18410/jebmh/2018/335
- Views 97
- Downloads 0
PREVALENCE OF DRY EYE SYNDROME IN PATIENTS WITH TYPE 1 AND TYPE 2 DIABETESA COMPARATIVE STUDY
BACKGROUND Diabetes mellitus (DM) is a major cause of various ocular complications including Keratoconjunctivitis sicca resulting in tear film deficiency, significantly hindering the performance of daily life and may lea...
CSF LACTATE IN MENINGITIS
BACKGROUND Meningitis is an infection within the subarachnoid space characterised by a CNS inflammatory reaction. It is a serious condition requiring immediate diagnosis and appropriate treatment to be started at the ear...
NIPPLE AREOLA COMPLEX INVOLVEMENT IN EARLY AND LATE CARCINOMA BREAST
The last several decades have witnessed significant advances in the surgical management of carcinoma breast. Many have embraced breast conservation as the procedure of choice in carefully selected patients. It provides e...
DIAGNOSIS AND MANAGEMENT OF CSF RHINORRHOEA – OUR EXPERIENCE
INTRODUCTION CSF rhinorrhoea is the leakage of clear watery fluid from the subarachnoid space into nasal and/or sinus cavities. CSF leak is a known potential complication with significant morbidity and mortality. It may...
CLINICO-PATHOLOGICAL CORRELATION OF LYMHADENOPATHY IN HIV POSITIVE PATIENTS
BACKGROUND: Lymphadenopathy is common in HIV infected individuals as lymphoid tissue is a major target and reservoir of the Human immunodeficiency virus (HIV) as well for opportunistic infections. AIM: Clinical assessmen...