Acute Oral Toxicity of Hydrofluoric Acid Controlled with Gq-300® Additive Fixed Dose Procedure-Acute Oral Toxicity -Ocde420
Journal Title: Advances in Clinical Toxicology - Year 2019, Vol 4, Issue 2
Abstract
This paper demonstrates the tolerable acute oral toxicity of a solution composed of Hydrofluoric acid (HF) at 24% concentration and GQ-300® as a controlling additive. The literature describes pure HF as a liquid, corrosive, colorless, fuming, (identifying CAS number 7664-39-3). GQ-300®, additive consisting of a strongly acidic chemical composition and safe for human use, obtained by the mixing of strong acids with the aim of achieving a balanced mixture of acids which allows, by means of additivation, the control and safe handling of other strong and corrosive acids commonly used in water treatment, cleaning of scale of silicates, in sites with contents of silicates to enhance recovery of metal, non-metal mining and hydrocarbon such as oil and gas. Since there is no precise information about the toxicity of this mixture, or it is expected that the test material is toxic, the study of oral toxicity uses varying volumes of fixed oral doses of three solutions of different concentrations of HF Controlled with the GQ - 300® additive Administered in rats in order to know the tolerable acute toxicity of the mixture. Obtaining as a result that the HF mixture controlled with GQ-300®, administered to rats wistar by mouth in a volume of 20 µl with a range of 275 to 289 mg/kg, have a tolerable dose of acute toxicity greater than the pure HF to 48% , which means that this GQ controller minimizes the toxic action of the HF.
Authors and Affiliations
Yasmin-Morales*, Yepsys-Montero, Andres-Osorio, Lewis Pozo, David Martucci and William Jimenez
Keywords
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- EP ID EP751654
- DOI 10.23880/act-16000152
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