Acute Renal Failure as Part of Multi-Organ Failure: How Long We Should Wait before We Intervene? A Dissection of Studies

Journal Title: Journal of Enam Meical College - Year 2015, Vol 5, Issue 1

Abstract

Mortality rate in multisystem organ failure (MOF) is very high. Acute renal failure is an important part of MOF. In this special feature article I have aimed to streamline the achievements of different studies on continuous renal replacement therapy (CRRT) for a fruitful outcome. For this I have gone for retrospective evaluation of the studies reached through PubMed, internet alert system of different journals, proceedings of conferences on CRRT and personal communication with the experts in this field. I have evaluated the outcome of studies to explore the causes of failure to achieve a positive result and to identify the positive gains of studies. Finally, I have compiled the positive gains to outline a new strategy for future study and greater achievement. The findings of evaluation led to the conclusion that while planning for initiation of CRRT, multiple strategies should be targeted. The strategy should involve early initiation of CRRT guided by new markers of acute kidney injury (AKI), continuous venovenous hemofiltration (CVVH) modality, optimum intensity (intensity should be adequate enough to improve hemodynamics within a targeted period), selection of an effective filter membrane. Elderly patients should be studied in a different group. Cardiac patients with AKI should not be studied in the same group along with the patients with sepsis.

Authors and Affiliations

Najib Mohammad

Keywords

Related Articles

Prescribing Pattern in Outpatient Departments of Two Tertiary Care Teaching Hospitals in Dhaka

Background: Medically inappropriate, ineffective and economically inefficient use of drugs is very common in our country. About 40% or more drugs expenditure may be wasted through irrational prescribing and dispensing....

Anemia in Patients with Chronic Obstructive Pulmonary Disease in a Tertiary Care Hospital in Bangladesh

Background: Chronic obstructive pulmonary disease (COPD) is usually associated with polycythemia. It is assumed that systemic inflammatory components of COPD can interfere with erythropoietin and can result in anemia of...

Unusual Foreign Body in Urinary Bladder: A Case Report

In the urinary tract, foreign body is most commonly found in the urinary bladder. It is commonly self-inflicted but can rarely be introduced by other person. Various types of foreign bodies have been reported, which incl...

A 29-Year-Old Male with Borderline Lepromatous Leprosy

Leprosy (Hansen’s disease) is a chronic granulomatous infectious disease that primarily affects the peripheral nerves, skin, upper respiratory tract mucosa, eyes and certain other tissues. It is diagnosable and curable...

Raised Vaginal Fluid Fibronectin Level Indicates Premature Rupture of Membrane

Background: Premature rupture of membrane (PROM) is one of the common complications of pregnancy that has major impact on fetal and neonatal outcome. It is the commonest clinical event where a normal pregnancy becomes...

Download PDF file
  • EP ID EP36219
  • DOI https://doi.org/10.3329/jemc.v5i1.21496
  • Views 352
  • Downloads 0

How To Cite

Najib Mohammad (2015). Acute Renal Failure as Part of Multi-Organ Failure: How Long We Should Wait before We Intervene? A Dissection of Studies. Journal of Enam Meical College, 5(1), -. https://europub.co.uk/articles/-A-36219