Acute Transfusion Reactions in Intensive Care Unit: A Retrospective Study
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 1
Abstract
Blood transfusion is a frequent and integral part of critical care. Although life saving it can occasionally be unsafe and results in spectrum of adverse events. Acute transfusion reactions (ATRs) are probably under diagnosed in critically ill patients due to confusion of the symptoms with the underlying disease. This was a retrospective review from Dec 2014 to Dec 2016. The ATRs related to the administration of blood components in the patients admitted to ICU for various reasons were recorded, analyzed and classified on the basis of their clinical features and laboratory tests. During the study period total of 3255 units of whole blood and component transfusion were carried out of which a total of 35(1.05%) ATRs were encountered. Packed Red Blood Cells (PRBCs) and whole blood were most commonly implicated. Allergic reactions were most frequent transfusion reaction noted, seen most commonly with PRBCs and whole blood. This was followed by febrile reactions which were seen most commonly with PRBCs. A rational use of blood and blood products considering their deleterious effects can decrease transfusion related mortality and morbidity in the critically ill patients.
Authors and Affiliations
Dr. S. Patil, Dr. L Patil, Dr. S Chavan
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