Acute Variceal Bleeding in Patients with Liver Cirrhosis with and without Diabetes
Journal Title: Liver Research – Open Journal - Year 2015, Vol 1, Issue 1
Abstract
Objectives: To study the effect of diabetes mellitus on presentations, course, and outcome of acute variceal bleeding in cirrhotic patients. Methods: We compared 2 matched groups of patients, a diabetic group and non-diabetic group, where all of the patients presented with acute esophageal varices due to liver cirrhosis. All patients underwent history taking, clinical examination, emergency treatment, upper endoscopy, laboratory investigations and abdominal ultrasound; they followed up until hospital discharge. Results: The diabetic group showed statistically significant unstable course in 73.3% of them compared to 36.6% in the control; more attacks of melena (2.2±1.03) compared to control (1.7±0.88), and also had significantly disturbed level of consciousness compared to control (36.7% versus 10% respectively); moreover they have significantly more right and left lobe enlargement than control (70% versus 26.7%, and 66.7 versus 40% respectively), significantly more echogenic liver (70% versus 33.3), highly significant more portal vein dilatations (73.3% versus 16.7%) and highly significant more collaterals (50% versus 23.3%); the splenic size was also significantly more enlarged in diabetics (60%) than control (40%), and the splenic vein diameter was significantly more dilated in diabetics (33.3%) versus control group (6.7%); finally the mortality was more in the diabetic group. Conclusions: Diabetic patients with acute variceal bleeding may show more morbidity and mortality rates.
Authors and Affiliations
Mohammad Mosaad
Keywords
Related Articles
- EP ID EP556434
- DOI 10.17140/LROJ-1-103
- Views 148
- Downloads 0
Comparisons between Portosystemic Shunting Modalities in Patients with Liver Cirrhosis and Portal Hypertension
During almost half of century period, in the Department of Surgery of Portal Hypertension and Pancreatoduodenal Zone of the JSC “Republican Specialized Center of Surgery (named after Academician V. Vakhidov”), portosyste...
Metastatic Liver Disease - Presenting as Multiple Hepatic Cysts
A 59 year-old woman with a history of successfully treated Hepatitis-C, Systemic Lupus Erythematosus, and a remote history of melanoma of the scalp presented to our center for evaluation of abdominal pain, nausea, vomiti...
The Prescribers’ Dilemma: Treatment of Hepatitis C Infection for Medicaid Insured Patients in United States
Introduction of Direct Acting Antivirals (DAA) to Hepatitis C Virus (HCV) treatment armamentarium has offered a great boost to the providers’ confidence to safely and effectively treat HCV infection in the majority of pa...
Acute Variceal Bleeding in Patients with Liver Cirrhosis with and without Diabetes
Objectives: To study the effect of diabetes mellitus on presentations, course, and outcome of acute variceal bleeding in cirrhotic patients. Methods: We compared 2 matched groups of patients, a diabetic group and non-dia...
“Cardiac Hepatopathy”: A Review of Liver Dysfunction in Heart Failure
The unique dual circulation of the liver confers relative protection against ischemic injury; however, low oxygen tension in the microcirculation (sinusoidal blood of the hepatic acinus) may render hepatocytes in zone 3...