Additional Surgical Procedures During Postchemotherapy Retroperitoneal Lymph Node Dissection in Patients with Nonseminomatous Testicular Tumor
Journal Title: Üroonkoloji Bülteni - Year 2016, Vol 15, Issue 2
Abstract
Objective: Retroperitoneal lymph node dissection (RLND) is frequently performed in non-seminomatous testicular tumor (TT) patients, especially in cases who have radiological residual mass despite normal tumor markers after chemotherapy (CT). On the other hand, additional surgical procedures may be required in post-CT patients during RLND due to high probability of severely invasion of residual mass to surrounding organs and major vascular structures. In this study, we aimed to evaluate the additional surgical procedures and complications during RLND. Materials and Methods: Between January 2000-July 2015, 63 metastatic non-seminomatous TT patients undergoing RLND due to residual mass after CT at our clinic were evaluated for additional surgical procedures during RLND. Age at surgery, localization of TT, clinic stage before CT, number of CT cycles, retroperitoneal mass size, duration of hospitalization, history of additional surgical procedures during surgery and RLND’s pathology of patients were evaluated. Clinic stage before CT was assessed according to 2009 tumor, node, metastasis staging system. For all patients, RLND was performed as right or left template according to localization of tumor. Results: The mean age of patients was 32.6±8.6 years. Additional surgical procedures were performed in 10 (15.9%) patients. In five patients, ipsilateral nephrectomy, in two patients vena cava excision and repair, in one patient aorta excision and replacement, in one patient ureteral segment excision and anastomosis and in one patient transverse colon resection were performed. On multivariate analysis, >5 cm mass size was determined to increase likelihood of significant additional surgical procedure (p=0.001, OR: 2.1, 95% CI: 1.088-4.202). Conclusion: For complete resection, the most common additional surgical procedure during surgery is nephrectomy following CT in RLND patients. However, major vascular procedures such as aort or vena cava excision and replacement may be required are need in more complex cases.
Authors and Affiliations
Nurullah Hamidi, Uygar Bağcı, Evren Süer, Mehmet İlker Gökçe, Kadir Türkölmez, Yaşar Bedük, Sümer Baltacı
Sentinel Lymph Node Biopsy in Lymphadenectomy for Prostate Cancer
Performing the sentinel lymph node (SLN) biopsy during prostate cancer staging aims to provide more accurate nodal staging with low complications than pelvic lymph node dissection. SLN might be found outside the extended...
The Effect of Sex and Age Differences on Pathology Results in Primary Bladder Cancer Patients
Objective: Bladder cancer is more frequently seen in males, whereas prognosis is usually worse in female patients. Although many factors affect the prognosis of urothelial carcinoma of bladder have been proposed, the eff...
Does the Future of Prostate Cancer Treatment Lie with Apoptotic Inducers?
Despite present-day clinical achievements which can extend the overall survival period, prostate cancer (PCa) related mortality remains a major problem. Resistance against apoptosis which consequently leads to disease pr...
Relationship Between Tumor Density in Radical Prostatectomy Material, Preoperative Predictive Factors and Biochemical Recurrence
Objective: In this study, we assessed the relationship between tumor density (tumor volume prostate volume ratio), preoperative predictive factors and biochemical recurrence (BR) in patients who underwent radical retropu...
Partial Urethrectomy for Female Urethral Transitional Epithelial Cell Carcinoma
To present a female case of partial urethrectomy and the following adjuvant chemo-radio-therapy for urethral transitional epithelial cell carcinoma originating from distal urethra in the light of literature. The patient...