Administration of Drug Induce Liver Injury to the Inpatients with Liver Disease
Journal Title: Indonesian Journal of Clinical Pharmacy - Year 2012, Vol 1, Issue 2
Abstract
Drug induced liver injury is a serious human health problems. Pre-existing liver diseases are risk factor of liver injury by the drugs. The study was conducted to evaluate the use of drug induced liver injury in patients hospitalized with liver disease at one hospital in Kota Tasikmalaya. Informations were collected retrospectively in the period 2010-2011 from the patient’s medical record. A total of 52 patients research subjects were discovered 50 patients (96%) using drug induced liver injury and 2 patients (4%) did not use it. Drug induced liver injury most widely used were ranitidine (31.3%), ceftriaxone (23.1%), and paracetamol (16.4%). Level of the DILI usage in patient with liver disease was relative high (96%). Further research is needed to determine the effect of the drug induced liver injury to liver injury.
Authors and Affiliations
Sindy E. Cinthya, Ivan S. Pradipta, Rizky Abdulah
Keywords
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