Administration of Drug Induce Liver Injury to the Inpatients with Liver Disease

Journal Title: Indonesian Journal of Clinical Pharmacy - Year 2012, Vol 1, Issue 2

Abstract

Drug induced liver injury is a serious human health problems. Pre-existing liver diseases are risk factor of liver injury by the drugs. The study was conducted to evaluate the use of drug induced liver injury in patients hospitalized with liver disease at one hospital in Kota Tasikmalaya. Informations were collected retrospectively in the period 2010-2011 from the patient’s medical record. A total of 52 patients research subjects were discovered 50 patients (96%) using drug induced liver injury and 2 patients (4%) did not use it. Drug induced liver injury most widely used were ranitidine (31.3%), ceftriaxone (23.1%), and paracetamol (16.4%). Level of the DILI usage in patient with liver disease was relative high (96%). Further research is needed to determine the effect of the drug induced liver injury to liver injury.

Authors and Affiliations

Sindy E. Cinthya, Ivan S. Pradipta, Rizky Abdulah

Keywords

Related Articles

Epidemiological and Experimental Studies: The Role of Metformin on Colorectal Cancer

GLOBOCAN data in 2012 showed colorectal cancer was the third leading cancer worldwide. In Indonesia, based on WHO data in 2014, colorectal cancer was the second common cancer ini men and third cancer in women. Epidemiol...

Potentially Inappropriate Medication Use for Geriatric Population in Bandung City

Analysis of potentially inappropriate medication in geriatric population is important to identify specific target risk-management strategies. This, however, is rarely conducted in Asian countries, especially in Indonesia...

The Influence of Antipsychotic to Decrease the Score of The Positive and Negative Syndrome Scale-Excited Component

Schizophrenia is a psychiatric disorder with one or more of the following criteria: delusions, hallucinations, ways of thinking and talking that is irregular, behavioral disorders and negative symptoms. The treatment res...

Potency of Drugs Interaction among Geriatric Patients Prescribing: Retrospective Study in Pharmacies in Bandung

Geriatric age is an age group that vulnerable to the problems which associated with drug use, one of them is the incidence of drug-drug interactions. This research, conducted to determine potential drug-drug interactions...

Medication Adherence among Hypertensive Patients in Primary Healthcare in Bandung City

Hypertension is a disease with high mortality and also mobility all over the world. The prevalence of hypertension is increasing every year and West Java is ranked fourth with a prevalence by 29.4%. This study aimed to m...

Download PDF file
  • EP ID EP333668
  • DOI -
  • Views 122
  • Downloads 0

How To Cite

Sindy E. Cinthya, Ivan S. Pradipta, Rizky Abdulah (2012). Administration of Drug Induce Liver Injury to the Inpatients with Liver Disease. Indonesian Journal of Clinical Pharmacy, 1(2), 43-48. https://europub.co.uk/articles/-A-333668