ADRENAL CORTICAL ADENOMA PRESENTING AS PRECOCIOUS PUBERTY IN A 7-YEAR-OLD GIRL- A CASE REPORT
Journal Title: INTERNATIONAL JOURNAL OF RESEARCH IN PATHOLOGY AND MICROBIOLOGY - Year 2018, Vol 2, Issue 2
Abstract
Childhood adrenocortical tumors (ACT) are rare entity. Because of the heterogeneity and rarity of the disease, prognostic factors have been difficult to establish in pediatric ACT. Most of the affected children are young girls with classic endocrine syndromes (virilizing and/or Cushing). The other presentation can be Conn syndrome, feminization and precocious puberty. Typical imaging findings of pediatric ACT consist of a large, well-defined suprarenal tumor containing calcifications with a thin capsule and no necrosis or hemorrhage. The pathologic classification of pediatric ACT is troublesome. Even an experienced pathologist can find it difficult to differentiate carcinoma from adenoma. In patients with localized and completely resected tumors, the size of the tumor has predictive value. Patients with large tumors (>500g) tend to behave aggressively with much higher relapse rate than those with small tumors. It is important for the clinicans and pathologists to be aware of these because of varied presentations.
Authors and Affiliations
Zamarak Noori, Jasvinder Kaur Bhatia, Harish Kumar, Ajay Malik
Keywords
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