ADRENAL CORTICAL ADENOMA PRESENTING AS PRECOCIOUS PUBERTY IN A 7-YEAR-OLD GIRL- A CASE REPORT
Journal Title: INTERNATIONAL JOURNAL OF RESEARCH IN PATHOLOGY AND MICROBIOLOGY - Year 2018, Vol 2, Issue 2
Abstract
Childhood adrenocortical tumors (ACT) are rare entity. Because of the heterogeneity and rarity of the disease, prognostic factors have been difficult to establish in pediatric ACT. Most of the affected children are young girls with classic endocrine syndromes (virilizing and/or Cushing). The other presentation can be Conn syndrome, feminization and precocious puberty. Typical imaging findings of pediatric ACT consist of a large, well-defined suprarenal tumor containing calcifications with a thin capsule and no necrosis or hemorrhage. The pathologic classification of pediatric ACT is troublesome. Even an experienced pathologist can find it difficult to differentiate carcinoma from adenoma. In patients with localized and completely resected tumors, the size of the tumor has predictive value. Patients with large tumors (>500g) tend to behave aggressively with much higher relapse rate than those with small tumors. It is important for the clinicans and pathologists to be aware of these because of varied presentations.
Authors and Affiliations
Zamarak Noori, Jasvinder Kaur Bhatia, Harish Kumar, Ajay Malik
Keywords
Related Articles
- EP ID EP656582
- DOI -
- Views 39
- Downloads 0
HISTOPATHOLOGICAL SPECTRUM OF TEMPORAL LOBE TUMORS; A 12 YEAR OBSERVATIONAL STUDY
The Central Nervous System tumor comprises ~2% of all the tumors, an overall increase has been observed especially in less developed countries. This increase in the incidence may be due to exposure of population to vario...
ASSESSMENT ON BACTERIOLOGICAL LOADS OF STREET SOLD FRUITS: MUSA ACUMINATA, MANGIFERA INDIKA AND PERSEA AMERICANA IN ARBA MINCH TOWN, SOUTH ETHIOPIA
Traditionally, fruit products have been regarded as microbiologically safer than other unprocessed foods. However, many outbreaks of human infections have been associated with the consumption of contaminated fruits. The...
A HISTOPATHOLOGICAL SPECTRUM OF OVARIAN LESIONS : AS STUDIED IN RIMS, A TERTIARY CARE HOSPITAL IN JHARKHAND
AIM: The aim of this study is to highlight the histopathological spectrum of ovarian both benign and malignant and to compare our study with findings of other centers. MATERIALS AND METHODS: Hematoxylin and eosin stained...
CLINICOPATHOLOGICAL SURVEY OF CARCINOMA UTERINE CERVIX IN PATIENTS ATTENDING TERTIARY CARE HOSPITAL OF CENTRAL UTTAR PRADESH
Carcinoma cervix is the third most common cancer in women worldwide and the commonest cause of mortality in developing countries. The present survey was conducted with the aim to study the different histopathological sub...
A CROSS SECTIONAL STUDY ON QUANTITATIVE & QUALITATIVE ALTERATION IN PLATELETS IN SYSTEMIC LUPUS ERYTHEMATOSUS (SLE).
Patient of SLE presents with wide range of clinical manifestations. Thrombocytopenia is a common hematological manifestations with prevalence ranging from 7to 30% in large series SLE patients and is an independent risk f...