Adult Attention-Deficit and Hyperactivity Disorder and Fibromyalgia: A Case-Control Study
Journal Title: Neuro – Open Journal - Year 2015, Vol 2, Issue 2
Abstract
Introduction: Fibromyalgia syndrome (FMS) is a disorder characterized by widespread musculoskeletal pain accompanied by fatigue, sleep, memory and mood issues. An association between attention deficit and fibromyalgia was reported. However, to our knowledge, there are few articles reporting an association between adult Attention Deficit Hyperactivity Disorder (ADHD) and FMS. We hypothesized that ADHD should be frequently associated with FMS. To confirm this hypothesis we conducted this study. Methods: Patients with Cognitive Complaint (CC) recruited from the membership of the Italian Hospital Medical Care Program in Argentina from 2009 to 2013 were classified as ADHD or without ADHD, and compared with Normal Controls (NC) about the presence of FMS. Adapted DSM-IV criteria for adult ADHD and validated to Spanish Wender Utah Rating Scale were used to identify individuals with adult ADHD. FMS was diagnosed according to Criteria Classification of Fibromyalgia of American College of Rheumatology of 1990. Analysis of categorical variables was carried out using chi-square. Mann-Whitney test was used for continuous variables. Statistical significance was P<0.05. Results: We identified 154 patients with ADHD, 71 NC, and 262 with CC without ADHD. Amongst ADHD cases, 37.7% were men, the median age was 72.5 years, in NC group, 40.8% were men with a mean age of 71.9, and in CC group, and 40% were men with a median age of 71.4 years. No significant differences in these variables between groups or in the years of education were found. Frequency of FMS was 24.7% in ADHD cases, 4.6% in CC group and 0% in NC. Prevalence of FMS in ADHD patients was significantly higher compared with other control groups (P<0.00001, 95% confidence interval extends from 0.0786 to 0.1330). Conclusion: In our sample, FMS is more prevalent in adult ADHD cases than in NC and CC patients as we expected. It should be done future studies to characterize the association of this disorders.
Authors and Affiliations
Golimstok Angel
Gaucher’s Disease, Myoclonic Seizures after Splenectomy: A Case Report
Gaucher’s Disease (GD) is the most prevalent lysosomal storage disorder, resulting from the accumulation of glucocerebrosidase in the cells of macrophagemonocyte system due to a deficiency in lysosomal glucocerebrosidase...
CNS Complication of Group A Streptococcal Meningitis in Children: a Comprehensive Case-Based Literature Review
Group A Streptococcus pyogenes meningitis rarely results in central nervous system complication. Chronic hydrocephalus is a well-known complication of bacterial meningitis. To date, no reports have focused on acute centr...
Wernicke Encephalopathy and Other Vitamin Deficiencies in a Patient with Home Parenteral Nutrition
Wernicke Encephalopathy (WE) is an acute and serious secondary neurological syndrome caused by a deficit of thiamine or vitamin B1. Although it rarely presents with the classic triad, the most frequent presenting symptom...
Audit of a Standard Operating Procedure to Prevent Wrong-Level Lumbar Spinal Surgery with Intra-Operative X-Ray
Introduction: One of the major errors that can be encountered by a spinal surgeon is operating at the wrong level/side. However, wrong-level spinal surgery is considered a ‘never-event’ and is under-reported. Many surgeo...
Stroke Mimics in the Pediatric Population
Pediatric stroke is a very rare condition and it is a cause of significant morbidity and mortality. It is among the top ten causes of death in the pediatric population, and over half of stroke survivors experience long-t...