Advance in immune microenvironment and immunotherapy in triple-negative breast cancer
Journal Title: Chinese Journal of Clinical Research - Year 2024, Vol 37, Issue 10
Abstract
Breast cancer is the most common malignant tumor in women. Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer, characterized by poor differentiation, high rate of progression and poor prognosis. Due to the lack of biomarkers, targeted therapy options for patients with TNBC are limited, and chemotherapy, radiotherapy, and surgical resection are currently the main treatment modalities. Since TNBC has a high tumor mutation burden and a high infiltration density of tumor-infiltrating lymphocytes, it may benefit patients from the treatment of immune checkpoint inhibitors (ICIs). This article focuses on the research of ICIs in TNBC, aiming to provide corresponding theoretical basis for the treatment of TNBC patients.
Authors and Affiliations
HU Yue, WANG Jialiang, HU Feixiang, GAO Rong, HONG Bo
Keywords
Related Articles
- EP ID EP749043
- DOI -
- Views 36
- Downloads 0
Fully automatic classification of lumbar disc degeneration based on deep learning
<b>Objective</b> To investigate the feasibility of a deep learning model for the fully automatic classification of disc degeneration based on lumbar structures on sagittal T2WI images. <b>Methods</b> The lumbar T2WI im...
Effects of laparoscopic surgery combined with hyperthermic intraperitoneal chemotherapy on postoperative coagulation indicators in patients with colorectal cancer
Objective To observe the changes of coagulation function in patients with colorectal cancer (CRC) after laparoscopic surgery combined with hyperthermic intraperitoneal chemotherapy (HIPEC). Methods Sixty patients with CR...
Clinical efficacy of minimally invasive transforaminal lumbar interbody fusion and endoscopic lumbar interbody fusion in the treatment of lumbar degenerative diseases
<b>Objective</b> To compare the safety and clinical efficacy of minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) and endoscopic lumbar interbody fusion (Endo-LIF) for lumbar degenerative diseases. <b...
Application of ultrasound-guided anterior quadratus lumborum block at the lateral supra-arcuate ligament in bariatric surgery
Objective To compare the analgesic effect of ultrasound-guided anterior quadratus lumborum block at the lateral supra-arcuate ligament (QLB-LSAL) and transversus abdominis plane block (TAPB) in laparoscopic sleeve gastr...
Summary of best evidence for rehabilitation timing in patients undergoing arthroscopic rotator cuff repair surgery
"<b>Objective</b> To search，organize,and summarize the best evidence of rehabilitation timing for patients after arthroscopic rotator cuff repair surgery, providing reference for clinical practice. <b>Methods</b> Da...