Adverse drug reaction monitoring in a teaching hospital Mandya
Journal Title: Indian Journal of Pharmacy and Pharmacology - Year 2018, Vol 5, Issue 1
Abstract
Objectives1nbspnbspnbspnbspnbspnbspnbsp To assess and analyse adverse drug reactions ADRs according to reporting and presentation2nbspnbspnbspnbspnbspnbspnbsp To describe causality and severity analysisMaterials and methods After taking approval from the Institutional ethical committee study was undertaken over a period of one year A prospective observational study was conducted to monitor the ADRs in all the clinical departments and emergency units of the hospital The ADRs forms were distributed to all the departments and informed them to report any suspected adverse drug reactions ADRs were monitored both actively and passively Reported forms were collected by active surveillance and Causality assessment was done by pharmacologist using Naranjorsquos amp WHO scale and severity by Hartwigrsquos scale respectivelyResults Total 85 ADRs were reported over a period of year Most of the ADRs were reported from the ART centers 706 The most common system involved in ADR was haematological system about 294 of overall reaction followed by 247 dermatological Zidovudine induced anaemia was the most common ADR Causality assessed using Naranjorsquos scale showed that most of reported ADRs were probable 494 271 were doubtful and 235 were possibleConclusion Study showed that there was under reporting of ADRs Most of the cases were reported from ART center There is a need to improve awareness among the clinicians to emphasize their role in voluntary reporting of ADRs on generating quality reports critically monitor the ADRs so as to prevent them furtherKeywords Adverse drug reaction Causality assessment Naranjo scale WHO scale and Hartwigrsquos scale
Authors and Affiliations
Drupad H. S. , Nagabushan H. , Rajeshwari
Keywords
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- EP ID EP478534
- DOI 10.18231/2393-9087.2018.0007
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