Aeroallergen Sensitivity Pattern in Poorly Controlled Asthmatics and its Relation to Asthma Control in a Tertiary Care Setting of Central Kerala, India
Journal Title: Journal of Clinical and Diagnostic Research - Year 2019, Vol 13, Issue 4
Abstract
ABSTRACT Introduction: Nasobronchial allergy is an exceedingly common problem in clinical practice. Estimates reveal that the prevalence of nasobronchial allergy is increasing worldwide, including in India. Sensitivity to individual aeroallergens varies depending on geography, genetic and environmental factors. Aim: To identify the sensitivity pattern to common aeroallergens in poorly controlled asthma patients and to correlate asthma severity with sensitivity to specific aeroallergens. Materials and Methods: A prospective cross-sectional study was conducted on out-patients attending the Department of Pulmonary Medicine with a diagnosis of asthma as per GINA guidelines. Patients above seven years with features of asthma were included in the study. The Asthma severity was assessed using the Asthma Control Test (ACT) questionnaire and lung function studies. SPT was performed as per clinical indication. The skin allergy sensitivity patterns were compared in groups as per their disease severity and level of control using Chi-square and Spearman rank correlation. Results: Patients with features of inadequately controlled asthma (ACT score less than 20 and FEV1 less than 80% predicted) showed a higher occurrence of positive reaction in the SPT to multiple aero and food allergens as compared with those having good ACT score and FEV1 >80%. Conclusion: Allergen sensitivity is very common in asthma. House dust mite, fungal allergens and grass pollens were the common allergen sensitisation identified in subjects with poorly controlled asthma. A correlation was seen between inadequately controlled asthma and sensitisation to multiple aeroallergens. So, vigorous allergen screening and allergen immunotherapy must be included in the management protocol of asthma.
Authors and Affiliations
Divya Ramachandran, Jolsana Augustine, EK Dhanya, Melcy Cleetus, AS Suramya, Rajesh Venkita Krishnan
Keywords
Related Articles
- EP ID EP553351
- DOI 10.7860/JCDR/2019/40854.12811
- Views 89
- Downloads 0
Substitutes of Prescription Medicines - A Review of Concerns Relevant to Doctors and Patients
A very large part of India’s population fulfils its healthcare needs from government run healthcare delivery system which is free, contributory or highly subsidised. Use of medicines forms a large part of healthcare faci...
Smartphone, the New Learning Aid amongst Medical Students
Introduction: The use of smartphone is increasing day by day for personal as well as professional purpose. They are becoming a more suitable tool for advancing education in developing countries. Mobile access to informat...
A 12-Week “Silver Yoga” Program Enhances Lung Function in Elderly Women Residents of a Hospice
ABSTRACT Introduction: “Silver Yoga” program has been devised by Centre for Yoga Therapy, Education and Research (CYTER) of Sri Balaji Vidyapeeth, Pondicherry. Participants practiced the protocol that was specially desig...
Retroperitoneal Teratoma Mimicking Renal Calculus
Images in Medicine
Evolving a Structural Model in Type 2 Diabetes Mellitus: Influence of Knowledge Attitudes, and Self-Management Practices on Glycaemic Control
ABSTRACT Introduction: Regularity in diabetes self-management practices among people with Type 2 Diabetes Mellitus (T2DM) is a predictor of glycaemic control. Knowledge and attitude have linear relationships with diabete...