AEROBIC BACTERIAL PROFILE OF DIABETIC ULCER IN A TERTIARY CARE CENTRE
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 68
Abstract
BACKGROUND Diabetes mellitus is one of the most challenging health problem in 21st century and fifth leading cause of death in developed countries.[1] Ulceration of foot is the most common problem affecting approximately 15% of diabetic patients during their lifetime. [2] The objective of the study was to find the aerobic bacterial profile of diabetic ulcer and to determine their antibiotic sensitivity pattern in a tertiary care centre. MATERIALS AND METHODS A total of 147 samples of diabetic ulcers were tested microbiologically using standard techniques and antimicrobial susceptibility testing was performed for the isolated pathogens using Kirby-Bauer disc diffusion method. RESULTS The rate of culture positivity was 100% and polymicrobial. Pseudomonas aeruginosa was the most frequent isolated pathogen (50.34%) followed by Escherichia coli (19.72%) and Klebsiella (19.04%). Gram-negative bacilli were highly sensitive to Imipenem and Meropenem. Among Staphylococci (29.92%), 17% were MRSA (Methicillin-Resistant Staphylococcus aureus). CONCLUSION Continuous surveillance of antibiotic susceptibility pattern of bacterial pathogen should be done to ensure rational use of antibiotics for empirical and definitive treatment of diabetic ulcer.
Authors and Affiliations
Sreekumary Puthusseril Kunjappan, Saju I. M
Keywords
Related Articles
- EP ID EP232610
- DOI 10.14260/Jemds/2017/1053
- Views 114
- Downloads 0
N-ACETYLCYSTEINE EFFECT ON GENTAMICIN INDUCED NEPHROTOXICITY IN ANIMAL MODELS
BACKGROUND Gentamicin exerts a unique pharmacokinetic effect on renal physiology and its use at high dose or prolonged treatment requires monitoring of kidney function test. Antioxidants has been claimed to have...
ASSOCIATION OF THYROID FUNCTION WITH BMI, BODY FAT % AND VISCERAL FAT LEVEL IN HEALTHY EUTHYROID INDIVIDUALS
BACKGROUND Obesity is known to be associated with altered thyroid function, increased risk of cardiovascular diseases, diabetes, insulin resistance and metabolic disorders. Thyroid hormones affect body weight through mod...
EVALUATION OF FINE NEEDLE ASPIRATION CYTOLOGY [FNAC] AS A SIMPLE AND EFFICIENT TOOL IN THE DIAGNOSIS OF THYROID LESIONS
BACKGROUND Fine Needle Aspiration Cytology (FNAC) has become the dominant method in the evaluation of thyroid swellings as it is a simple, minimally-invasive procedure which provides quick and reliable reports, thereby h...
A COMPARATIVE STUDY OF CLONIDINE AND DEXMEDETOMIDINE AS AN ADJUVANT IN SUPRACLAVICULAR BRACHIAL PLEXUS BLOCK
BACKGROUND Supraclavicular block provides anaesthesia for upper extremity in the most consistent andf efficient manner of any brachial plexus technique. Adjuvants when added to local anaesthetics enhance the onset and pr...
ANTIBIOGRAM OF ENTEROCOCCAL SPECIES ISOLATED FROM CLINICAL SPECIMENS IN A TERTIARY CARE TEACHING HOSPITAL
BACKGROUND Enterococci are Gram-positive cocci that are normal inhabitants of the gastrointestinal tract. Enterococci have become the second most common agent recovered from nosocomial UTI and wound infections a...