„Obesity Paradox“ – Fiction or a Fact?
Journal Title: Macedonian Journal of Medical Sciences (MJMS) - Year 2013, Vol 6, Issue 3
Abstract
Background: Many cardiovascular diseases are associated with obesity, but, despite this fact, obese people live longer than their normal-weight counterparts do. This phenomenon is called the „obesity paradox“. Aim: Purpose was to investigate the impact of obesity on the final outcome; determine the connection between obesity and heart rate > 80 beats per minute and other risk factors, and presence of „obesity paradox“. Material and Methods: Research included 140 patients with anterior wall acute STEMI treated in Coronary Unit, Clinical Center Kragujevac form January 2001-June 2006. Heart rate was calculated as the mean value of baseline and heart rate in the first 30 minutes after admission. Body mass index was calculated as the ratio of body weight in kilograms and body height in squared meters, and classified according to the WHO recomendations. Results: More than 75% obese patients were in both groups, survivors and those who died. In the subgroup with heart rate > 80 results were similar. Obesity had no significant effect on mortality despite the fact that the large number of patients with fatal outcome was obese. Conclusion: Correlation with acute myocardial infarction and elevated heart rate is evident, but obesity was not independent predictor for mortality which can only partly confirm presence of „obesity paradox“.
Authors and Affiliations
Goran Davidovic| Clinic for Cardiology, Clinical Center Kragujevac, Kragujevac, Serbia; Facult of Medical Sciences, University in Kragujevac, Kragujevac, Serbia, Violeta Iric-Cupic| Clinic for Cardiology, Clinical Center Kragujevac, Kragujevac, Serbia; Facult of Medical Sciences, University in Kragujevac, Kragujevac, Serbia, Srdjan Milanov| Faculty of Medical Sciences, University in Kragujevac, Kragujevac, Serbia, Ivan Simic| Clinic for Cardiology, Clinical Center Kragujevac, Kragujevac, Serbia; Facult of Medical Sciences, University in Kragujevac, Kragujevac, Serbia, Ziva Zivic| Center of Gastroenterohepatolology, Internal Clinic, Clinical Center Kragujevac, Kragujevac, Serbia, Mirjana Janicijevic-Petrovic| Clinic for Cardiology, Clinical Center Kragujevac, Kragujevac, Serbia; Clinic of Ophtalmology, Clinical Cent er Kragujevac, Kragujevac, Serbia
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