Aggressive Fibromatosis of the Chest Wall Mimicking Low Grade Fibrosarcoma – An Unusual Clinical Presentation
Journal Title: International Journal of Health Sciences and Research - Year 2017, Vol 7, Issue 8
Abstract
Background: Aggressive fibromatosis (AF), also known as desmoid tumour or musculoaponeurotic fibromatosis, is a monoclonal fibroblastic proliferative disease. It can present as abdominal and extra-abdominal fibromatosis. Extra abdominal deep fibromatosis represent 3.5% of fibrous tissue tumor and 0.03% of all neoplasms. Anterior chest wall forms 10% of Extra abdominal deep fibromatosis cases. Case history: Patient presented with a progressively increasing large swelling on the chest wall since 2 years. On examination, firm to hard ill defined growth was found. Microscopic examination showed a cellular spindle cell tumour. Strong positivity for VIMENTIN and focal positivity for SMA and DESMIN was seen on Immunohistochemistry. Final Diagnosis of aggressive fibromatosis was made. Conclusion: This case is being presented for its rarity, unusual clinical presentation and overlapping clinical and histopathological features with fibrosarcoma, which is a malignant entity.
Authors and Affiliations
Dr. Nimisha Sharma
Keywords
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